Difference between revisions of "SigF"
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** ''[[spoIIAA]]'': activated by [[Spo0A]] and repressed by [[SinR]] | ** ''[[spoIIAA]]'': activated by [[Spo0A]] and repressed by [[SinR]] | ||
** [[Spo0A]]: transcription activation [http://www.ncbi.nlm.nih.gov/sites/entrez/1556084,15687200 PubMed] | ** [[Spo0A]]: transcription activation [http://www.ncbi.nlm.nih.gov/sites/entrez/1556084,15687200 PubMed] | ||
| + | ** [[AbrB]]: transcription repression {{PubMed|20817675}} | ||
* '''Additional information:''' | * '''Additional information:''' | ||
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<pubmed>20833318 </pubmed> | <pubmed>20833318 </pubmed> | ||
==Original Publications== | ==Original Publications== | ||
| − | <pubmed>10503549,8358793,7570023,9555886,3007937,8460142,9077448,10323866,10869437,7768847,14744853,8759874,10864495,1744043,16824103,11701124,1902463,8171000,1904527,15351644,15882622,8764398,8764397,16497325,9826498,9826499,2492512,1629150,12676949,7592342,11684022,8846916,1948031,8126438,3114419,12081956,9150232,15205443,9004507,8168129,2123551,8824593,19390092,17498739,8021191,1556084,15687200,12107147, 20298743 18208527 10049355 </pubmed> | + | <pubmed>10503549,8358793,7570023,9555886,3007937,8460142,9077448,10323866,10869437,7768847,14744853,8759874,10864495,1744043,16824103,11701124,1902463,8171000,1904527,15351644,15882622,8764398,8764397,16497325,9826498,9826499,2492512,1629150,12676949,7592342,11684022,8846916,1948031,8126438,3114419,12081956,9150232,15205443,9004507,8168129,2123551,8824593,19390092,17498739,8021191,1556084,15687200,12107147, 20298743 18208527 10049355 20817675</pubmed> |
[[Category:Protein-coding genes]] | [[Category:Protein-coding genes]] | ||
Revision as of 19:55, 15 September 2010
- Description: RNA polymerase forespore-specific (early) sigma factor SigF
| Gene name | sigF |
| Synonyms | spoIIAC |
| Essential | no |
| Product | RNA polymerase forespore-specific (early) sigma factor SigF |
| Function | transcription of sporulation genes (late mother cell) |
| Metabolic function and regulation of this protein in SubtiPathways: Stress | |
| MW, pI | 29 kDa, 5.078 |
| Gene length, protein length | 765 bp, 255 aa |
| Immediate neighbours | spoVAA, spoIIAB |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
| |
Contents
The gene
Basic information
- Locus tag: BSU23450
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family: sigma-70 factor family (according to Swiss-Prot)
- Paralogous protein(s):
Genes controlled by SigF
dacF-spoIIAA-spoIIAB-sigF, sigG, pbpF, yphA-seaA
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Localization: cell membrane (according to Swiss-Prot)
Database entries
- Structure: 1L0O (complex with SpoIIAB, Geobacillus stearothermophilus)
- UniProt: P07860
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
- Charles Moran, Emory University, NC, USA homepage
Your additional remarks
References
Reviews
Michiel J L de Hoon, Patrick Eichenberger, Dennis Vitkup
Hierarchical evolution of the bacterial sporulation network.
Curr Biol: 2010, 20(17);R735-45
[PubMed:20833318]
[WorldCat.org]
[DOI]
(I p)
Original Publications
