Difference between revisions of "NagZ"

From SubtiWiki
Jump to: navigation, search
(References)
(References)
Line 120: Line 120:
  
 
=References=
 
=References=
<pubmed>10627040, 20400549 4628806 4196675 </pubmed>
+
<pubmed>10627040, 20400549 4628806 4196675 20826810</pubmed>
 
[[Category:Protein-coding genes]]
 
[[Category:Protein-coding genes]]

Revision as of 11:04, 15 September 2010

  • Description: N-acetylglucosaminidase

Gene name nagZ
Synonyms yzbA, ybbD
Essential no
Product N-acetylglucosaminidase
Function cell wall recycling
MW, pI 70 kDa, 9.76
Gene length, protein length 1926 bp, 642 aa
Immediate neighbours ybbC, amiE
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
YbbD context.gif
This image was kindly provided by SubtiList



The gene

Basic information

  • Locus tag: BSU01660

Phenotypes of a mutant

increased autolysis PubMed

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: cleaves muropeptides derived from peptidoglycan, but not peptidoglycan itself PubMed
  • Protein family: glycosyl hydrolase 3 family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization: secreted (with signal peptide), remains to some extent cell wall-associated PubMed

Database entries

  • KEGG entry: [2]
  • E.C. number:

Additional information

The gene is mis-annotated in KEGG as an ortholog of beta-N-acetylhexosaminidase EC 3.2.1.52. It is marked in MetaCyc as “similar to beta-hexosaminidase”. No EC annotation is available in Swiss-ProtSwiss-Prot.supporting the annotation is available. PubMed

Expression and regulation

  • Operon:
  • Regulation:
    • expressed in late exponential and early stationary phase PubMed
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References