Difference between revisions of "SsbA"
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=Expression and regulation= | =Expression and regulation= | ||
| + | * '''Operon:''' ''[[yyaF]]-[[rpsF]]-[[ssbA]]-[[rpsR]]'' {{PubMed|14762004}} | ||
| − | * ''' | + | * '''Sigma factor:''' |
| − | |||
| − | |||
* '''Regulation:''' | * '''Regulation:''' | ||
** [[RelA]] dependent downregulation (Class I) during stringent response {{PubMed|11948165}} | ** [[RelA]] dependent downregulation (Class I) during stringent response {{PubMed|11948165}} | ||
| − | + | ** [[ComK]]: transcription activation {{PubMed|11948146}} | |
| − | * | ||
* '''Additional information:''' | * '''Additional information:''' | ||
| Line 121: | Line 119: | ||
=References= | =References= | ||
| − | <pubmed>17853894,19730681 ,16479537, 16549871 20122408 </pubmed> | + | <pubmed>17853894,19730681 11948146,16479537,11948165 16549871 20122408 14762004</pubmed> |
[[Category:Protein-coding genes]] | [[Category:Protein-coding genes]] | ||
Revision as of 11:24, 13 February 2010
- Description: single-strand DNA-binding protein, part of the replisome
| Gene name | ssbA |
| Synonyms | ssb |
| Essential | yes PubMed |
| Product | single-strand DNA-binding protein |
| Function | DNA replication, recombination, repair |
| MW, pI | 18 kDa, 4.822 |
| Gene length, protein length | 516 bp, 172 aa |
| Immediate neighbours | rpsR, rpsF |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
| |
Contents
The gene
Basic information
- Locus tag: BSU40900
Phenotypes of a mutant
essential PubMed
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family:
- Paralogous protein(s): SsbB
Extended information on the protein
- Kinetic information:
- Domains:
- Cofactor(s):
- Effectors of protein activity: Phosphorylation of Ssb increases binding to single-stranded DNA in vitro almost 200-fold PubMed
- Interactions: part of the replisome: PolC-HolA-HolB-DnaX-DnaN-DnaG-DnaC-DnaI-DnaD-SsbA-DnaE-PriA-DnaB PubMed
- Localization: Nucleoid (Mid-cell) PubMed
Database entries
- Structure:
- UniProt: P37455
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Sigma factor:
- Regulation:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
