Difference between revisions of "AraA"
(→Extended information on the protein) |
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=Expression and regulation= | =Expression and regulation= | ||
| + | * '''Operon:''' ''[[araA]]-[[araB]]-[[araD]]-[[araL]]-[[araM]]-[[araN]]-[[araP]]-[[araQ]]-[[abfA]]'' {{PubMed|9084180}} | ||
| − | * ''' | + | * '''[[Sigma factor]]:''' [[SigA]] {{PubMed|9084180}} |
| − | * '''[[ | + | * '''Regulation:''' |
| + | ** repressed by glucose ([[CcpA]]) {{PubMed|12949161}} | ||
| + | ** induced by arabinose ([[AraR]]) [http://www.ncbi.nlm.nih.gov/sites/entrez/10417639 PubMed] | ||
| − | * ''' | + | * '''Regulatory mechanism:''' |
| − | ** | + | ** [[CcpA]]: transcription repression {{PubMed|12949161}} |
| − | |||
| − | |||
** [[AraR]]: transcription repression [http://www.ncbi.nlm.nih.gov/sites/entrez/10417639 PubMed] | ** [[AraR]]: transcription repression [http://www.ncbi.nlm.nih.gov/sites/entrez/10417639 PubMed] | ||
Revision as of 20:28, 16 December 2009
- Description: L-arabinose isomerase
| Gene name | araA |
| Synonyms | |
| Essential | no |
| Product | L-arabinose isomerase |
| Function | arabinose utilization |
| Metabolic function and regulation of this protein in SubtiPathways: Sugar catabolism | |
| MW, pI | 56 kDa, 5.474 |
| Gene length, protein length | 1494 bp, 498 aa |
| Immediate neighbours | araB, abnA |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
| |
Contents
The gene
Basic information
- Locus tag: BSU28800
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: L-arabinose = L-ribulose (according to Swiss-Prot)
- Protein family: arabinose isomerase family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information: k (cat) of 14,504 min(-1) and k (cat)/K (m) of 121 min(-1) mM(-1) for L-arabinose PubMed
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Interactions:
- Localization:
Database entries
- Structure:
- UniProt: P94523
- KEGG entry: [3]
- E.C. number: 5.3.1.4
Additional information
Expression and regulation
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
