Difference between revisions of "SpoIVFB"
| Line 89: | Line 89: | ||
=Expression and regulation= | =Expression and regulation= | ||
| − | * '''Operon:''' | + | * '''Operon:''' ''[[spoIVFA]]-[[spoIVFB]]'' {{PubMed|1942049}} |
| − | * '''[[Sigma factor]]:''' [[SigE]] {{PubMed|15699190}} | + | * '''[[Sigma factor]]:''' [[SigE]] {{PubMed|15699190,1942049}} |
* '''Regulation:''' | * '''Regulation:''' | ||
| + | ** expressed early during sporulation in the mother cell ([[SigE]], [[SpoIIID]]) {{PubMed|15699190,1942049,15383836}} | ||
* '''Regulatory mechanism:''' | * '''Regulatory mechanism:''' | ||
| + | ** [[SpoIIID]]: transcription repression {{PubMed|15383836}} | ||
* '''Additional information:''' | * '''Additional information:''' | ||
| Line 119: | Line 121: | ||
=References= | =References= | ||
| − | <pubmed>11959848,9501233,12940997,1577688,12060714,9078383,1942049,10611287, 16818230 19805276 </pubmed> | + | <pubmed>11959848,9501233,12940997,1577688,12060714,9078383,1942049,10611287,15383836 16818230 19805276 15699190</pubmed> |
[[Category:Protein-coding genes]] | [[Category:Protein-coding genes]] | ||
Revision as of 19:04, 13 December 2009
- Description: intramembrane metalloprotease, processing of pro-sigma-K to active SigK
| Gene name | spoIVFB |
| Synonyms | |
| Essential | no |
| Product | intramembrane metalloprotease |
| Function | processing of pro-sigma-K to active SigK |
| MW, pI | 33 kDa, 8.483 |
| Gene length, protein length | 864 bp, 288 aa |
| Immediate neighbours | rplU, spoIVFA |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
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Contents
The gene
Basic information
- Locus tag: BSU27970
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Protein family: peptidase M50B family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- C-terminal cystathionine-beta-synthase (CBS) domain, this domain binds ATP PubMed
- Modification:
- Cofactor(s):
- Effectors of protein activity: ATP regulates substrate access to the active site and renders cleavage sensitive to the cellular energy level PubMed
- Localization: cell membrane
Database entries
- Structure:
- UniProt: P26937
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
