Difference between revisions of "RapF"
| Line 1: | Line 1: | ||
| − | * '''Description:''' response regulator aspartate phosphatase <br/><br/> | + | * '''Description:''' response regulator aspartate phosphatase, controls [[ComA]] activity <br/><br/> |
{| align="right" border="1" cellpadding="2" | {| align="right" border="1" cellpadding="2" | ||
| Line 12: | Line 12: | ||
|style="background:#ABCDEF;" align="center"| '''Product''' || response regulator aspartate phosphatase | |style="background:#ABCDEF;" align="center"| '''Product''' || response regulator aspartate phosphatase | ||
|- | |- | ||
| − | |style="background:#ABCDEF;" align="center"|'''Function''' || control of | + | |style="background:#ABCDEF;" align="center"|'''Function''' || control of [[ComA]] activity |
|- | |- | ||
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 45 kDa, 5.18 | |style="background:#ABCDEF;" align="center"| '''MW, pI''' || 45 kDa, 5.18 | ||
| Line 52: | Line 52: | ||
=== Basic information/ Evolution === | === Basic information/ Evolution === | ||
| − | * '''Catalyzed reaction/ biological activity:''' | + | * '''Catalyzed reaction/ biological activity:''' control of [[ComA]] activity {{PubMed|15968044}} |
* '''Protein family:''' RAP family (according to Swiss-Prot) | * '''Protein family:''' RAP family (according to Swiss-Prot) | ||
| Line 68: | Line 68: | ||
* '''Cofactor(s):''' | * '''Cofactor(s):''' | ||
| − | * '''Effectors of protein activity:''' | + | * '''Effectors of protein activity:''' binding of [[PhrF]] to [[RapF]] prevents it from binding [[ComA]] {{PubMed|15968044}} |
| − | * '''Interactions:''' | + | * '''Interactions:''' [[RapF]]-[[ComA]] {{PubMed|15968044}}, [[RapF]]-[[PhrF]] {{PubMed|15968044}} |
| − | * '''Localization:''' | + | * '''Localization:''' |
=== Database entries === | === Database entries === | ||
| Line 118: | Line 118: | ||
=References= | =References= | ||
| − | <pubmed>12850135, </pubmed> | + | <pubmed>12850135, 15968044</pubmed> |
[[Category:Protein-coding genes]] | [[Category:Protein-coding genes]] | ||
Revision as of 08:15, 29 November 2009
- Description: response regulator aspartate phosphatase, controls ComA activity
| Gene name | rapF |
| Synonyms | ywhJ |
| Essential | no |
| Product | response regulator aspartate phosphatase |
| Function | control of ComA activity |
| MW, pI | 45 kDa, 5.18 |
| Gene length, protein length | 1143 bp, 381 aa |
| Immediate neighbours | ywhK, phrF |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
| |
Contents
The gene
Basic information
- Locus tag: BSU37460
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Protein family: RAP family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Localization:
Database entries
- Structure:
- UniProt: P71002
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Operon:
- Regulatory mechanism: CcpA: transcription repression
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Cristina Bongiorni, Shu Ishikawa, Sophie Stephenson, Naotake Ogasawara, Marta Perego
Synergistic regulation of competence development in Bacillus subtilis by two Rap-Phr systems.
J Bacteriol: 2005, 187(13);4353-61
[PubMed:15968044]
[WorldCat.org]
[DOI]
(P p)
Hans-Matti Blencke, Georg Homuth, Holger Ludwig, Ulrike Mäder, Michael Hecker, Jörg Stülke
Transcriptional profiling of gene expression in response to glucose in Bacillus subtilis: regulation of the central metabolic pathways.
Metab Eng: 2003, 5(2);133-49
[PubMed:12850135]
[WorldCat.org]
[DOI]
(P p)
