Difference between revisions of "AnsR"

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* '''Description:''' transcription repressor of the ''ansAB'' operon<br/><br/>
+
* '''Description:''' transcription repressor of the ''[[ansA]]-[[ansB]]'' operon<br/><br/>
  
 
{| align="right" border="1" cellpadding="2"  
 
{| align="right" border="1" cellpadding="2"  
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|style="background:#ABCDEF;" align="center"| '''Essential''' || no  
 
|style="background:#ABCDEF;" align="center"| '''Essential''' || no  
 
|-
 
|-
|style="background:#ABCDEF;" align="center"| '''Product''' || transcriptional regulator (Xre family)
+
|style="background:#ABCDEF;" align="center"| '''Product''' || transcriptional regulator ([[Xre family]])
 
|-
 
|-
 
|style="background:#ABCDEF;" align="center"|'''Function''' || negative regulation of the ''[[ansA]]-[[ansB]]'' operon
 
|style="background:#ABCDEF;" align="center"|'''Function''' || negative regulation of the ''[[ansA]]-[[ansB]]'' operon
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=Expression and regulation=
 
=Expression and regulation=
  
* '''Operon:''' ''ansR''
+
* '''Operon:''' ''ansR'' {{PubMed|8478318}}
  
 
* '''Sigma factor:'''  
 
* '''Sigma factor:'''  
  
 
* '''Regulation:'''  
 
* '''Regulation:'''  
 +
** induced in the presence of asparagine ([[AnsR]]){{PubMed|11914346}}
  
 
* '''Regulatory mechanism:'''  
 
* '''Regulatory mechanism:'''  
 +
** [[AnsR]]: negative autoregulation {{PubMed|11914346}}
  
 
* '''Additional information:'''
 
* '''Additional information:'''
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=References=
 
=References=
  
<pubmed>8478318,, </pubmed>
+
<pubmed>8478318,11914346 , </pubmed>
  
 
[[Category:Protein-coding genes]]
 
[[Category:Protein-coding genes]]

Revision as of 20:08, 18 November 2009

  • Description: transcription repressor of the ansA-ansB operon

Gene name ansR
Synonyms
Essential no
Product transcriptional regulator (Xre family)
Function negative regulation of the ansA-ansB operon
Metabolic function and regulation of this protein in SubtiPathways:
Asp, Asn
MW, pI 13 kDa, 4.807
Gene length, protein length 348 bp, 116 aa
Immediate neighbours ansA, yqxK
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
AnsR context.gif
This image was kindly provided by SubtiList







The gene

Basic information

  • Locus tag: BSU23590

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization: cytoplasm (according to Swiss-Prot)

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Sigma factor:
  • Regulation:
    • induced in the presence of asparagine (AnsR)PubMed
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Susan H Fisher, Lewis V Wray
Bacillus subtilis 168 contains two differentially regulated genes encoding L-asparaginase.
J Bacteriol: 2002, 184(8);2148-54
[PubMed:11914346] [WorldCat.org] [DOI] (P p)

D Sun, P Setlow
Cloning and nucleotide sequence of the Bacillus subtilis ansR gene, which encodes a repressor of the ans operon coding for L-asparaginase and L-aspartase.
J Bacteriol: 1993, 175(9);2501-6
[PubMed:8478318] [WorldCat.org] [DOI] (P p)