Difference between revisions of "KdgA"
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=Expression and regulation= | =Expression and regulation= | ||
| − | * '''Operon:''' | + | * '''Operon:''' ''[[kdgR]]-[[kdgK]]-[[kdgA]]-[[kdgT]]'' {{PubMed|9846747}} |
| − | * '''[[Sigma factor]]:''' | + | * '''[[Sigma factor]]:''' [[SigA]] {{PubMed|9846747}} |
| − | * '''Regulation:''' repressed by glucose ([[CcpA]]) | + | * '''Regulation:''' |
| + | ** induced by galacturonate ([[KdgR]]) {{PubMed|9846747}} | ||
| + | ** repressed by glucose ([[CcpA]]) {{PubMed|9846747}} | ||
| − | * '''Regulatory mechanism:''' [[CcpA]]: transcription repression | + | * '''Regulatory mechanism:''' |
| + | ** [[KdgR]]: transcription repression {{PubMed|9846747}} | ||
| + | ** [[CcpA]]: transcription repression {{PubMed|9846747}} | ||
| − | * '''Additional information:''' | + | * '''Additional information:''' |
=Biological materials = | =Biological materials = | ||
Revision as of 20:29, 26 October 2009
- Description: 2-dehydro-3-deoxy-phosphogluconate aldolase
| Gene name | kdgA |
| Synonyms | |
| Essential | no |
| Product | 2-dehydro-3-deoxy-phosphogluconate aldolase |
| Function | utilization of galacturonic acid |
| MW, pI | 20 kDa, 5.273 |
| Gene length, protein length | 588 bp, 196 aa |
| Immediate neighbours | kdgT, kdgK |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
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Contents
The gene
Basic information
- Locus tag: BSU22100
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: 4-hydroxy-2-oxoglutarate = pyruvate + glyoxylate (according to Swiss-Prot)
- Protein family: anti-sigma-factor family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Interactions:
- Localization: cell membrane (according to Swiss-Prot)
Database entries
- Structure:
- UniProt: P50846
- KEGG entry: [3]
- E.C. number: 4.1.3.16
Additional information
Expression and regulation
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Petar Pujic, Rozenn Dervyn, Alexei Sorokin, S Dusko Ehrlich
The kdgRKAT operon of Bacillus subtilis: detection of the transcript and regulation by the kdgR and ccpA genes.
Microbiology (Reading): 1998, 144 ( Pt 11);3111-3118
[PubMed:9846747]
[WorldCat.org]
[DOI]
(P p)
