Difference between revisions of "MtlA"
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=== Database entries === | === Database entries === | ||
| − | * '''DBTBS entry:''' | + | * '''DBTBS entry:''' [http://dbtbs.hgc.jp/COG/prom/mtlAD.html] |
* '''SubtiList entry:''' [http://genolist.pasteur.fr/SubtiList/genome.cgi?gene_detail+BG11215] | * '''SubtiList entry:''' [http://genolist.pasteur.fr/SubtiList/genome.cgi?gene_detail+BG11215] | ||
| Line 92: | Line 92: | ||
=Expression and regulation= | =Expression and regulation= | ||
| − | * '''Operon:''' ''[[mtlA]]-[[mtlD]]'' | + | * '''Operon:''' ''[[mtlA]]-[[mtlD]]'' {{PubMed|12897001}} |
* '''[[Sigma factor]]:''' | * '''[[Sigma factor]]:''' | ||
Revision as of 18:47, 20 August 2009
- Description: trigger enzyme: mannitol-specific phosphotransferase system, EIICBA
| Gene name | mtlA |
| Synonyms | |
| Essential | no |
| Product | trigger enzyme: mannitol-specific phosphotransferase system, EIICBA |
| Function | mannitol uptake and phosphorylation, control of MtlR activity |
| Metabolic function and regulation of this protein in SubtiPathways: Sugar catabolism | |
| MW, pI | 65 kDa, 8.778 |
| Gene length, protein length | 1830 bp, 610 aa |
| Immediate neighbours | ycnL, mtlD |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
| |
Contents
The gene
Basic information
- Locus tag: BSU03981
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: Protein EIIA N(pi)-phospho-L-histidine + protein EIIB = protein EIIA + protein EIIB N(pi)-phospho-L-histidine/cysteine (according to Swiss-Prot)
- Protein family: PTS permease, fructose/ mannitol permease (Fru) family PubMed
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification: phosphorylation on Ser-559 PubMed
- Cofactor(s):
- Effectors of protein activity:
- Localization: cell membrane (according to Swiss-Prot)
Database entries
- Structure:
- UniProt: P42956
- KEGG entry: [3]
- E.C. number: 2.7.1.69
Additional information
Expression and regulation
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
