YlyB

• Description: similar to pseudouridylate synthase
  
  

Gene name	ylyB
Synonyms	ylmL
Essential	no
Product	unknown
Function	unknown
MW, pI	33 kDa, 5.431
Gene length, protein length	909 bp, 303 aa
Immediate neighbours	lspA, pyrR
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList

The gene

Basic information

• Locus tag: BSU15460

Database entries

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity: RNA uridine = RNA pseudouridine (according to Swiss-Prot)

• Protein family: S4 RNA-binding domain (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:

Database entries

• Structure: 2I82 (the E. coli enzyme) PubMed

• UniProt: Q45480

• KEGG entry: [2]

• E.C. number:

Expression and regulation

• Operon:

• Sigma factor:

• Regulation:

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Charmaine Hoang, Junjun Chen, Caroline A Vizthum, Jason M Kandel, Christopher S Hamilton, Eugene G Mueller, Adrian R Ferré-D'Amaré
Crystal structure of pseudouridine synthase RluA: indirect sequence readout through protein-induced RNA structure.
Mol Cell: 2006, 24(4);535-45
[PubMed:17188032] [WorldCat.org] [DOI] (P p)