Difference between revisions of "Tpi"
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=== Database entries === | === Database entries === | ||
− | * '''Structure:''' [http://www.ncbi.nlm.nih.gov/Structure/mmdb/mmdbsrv.cgi?Dopt=s&uid=48255 NCBI] | + | * '''Structure:''' complex with 2-phosphpoglycolic acid, ''Geobacillus stearothermophilus'' [http://www.ncbi.nlm.nih.gov/Structure/mmdb/mmdbsrv.cgi?Dopt=s&uid=48255 NCBI] |
* '''Swiss prot entry:''' [http://www.expasy.ch/cgi-bin/sprot-search-ac?P27876] | * '''Swiss prot entry:''' [http://www.expasy.ch/cgi-bin/sprot-search-ac?P27876] |
Revision as of 12:42, 8 January 2009
- Description: catalyzes the transformation of glycerinaldehyd 3-phosphate to dihydroxyactonphosphate and the reverse reaktion
Gene name | tpi |
Synonyms | tpiA |
Essential | yes |
Product | Triosephosphate isomerase |
Function | isomerase |
MW, pI | 26,9 kDa, 4.79 |
Gene length, protein length | 759 bp, 253 amino acids |
Immediate neighbours | pgk, pgm |
Gene sequence (+200bp) | Protein sequence |
Genetic context File:GenE context.gif |
Contents
The gene
Basic information
- Coordinates:
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: D-glyceraldehyde 3-phosphate = glycerone phosphate
- Protein family: triosephosphate isomerase family
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification: phosphorylation PubMed
- Cofactor(s):
- Effectors of protein activity:
- Interactions: Pgm-TpiA
- Localization: Cytoplasm PubMed
Database entries
- Structure: complex with 2-phosphpoglycolic acid, Geobacillus stearothermophilus NCBI
- Swiss prot entry: [3]
- KEGG entry: [4]
- E.C. number: [5]
Additional information
Expression and regulation
- Sigma factor: SigA
- Regulation: neg. regulated by CggR, induced by sugar
- Regulatory mechanism: repressor CggR
- Additional information:
Biological materials
Labs working on this gene/protein
Your additional remarks
References
- Author1, Author2 & Author3 (year) Title Journal volume: page-page. PubMed