Difference between revisions of "Epr"

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Line 93: Line 93:
  
 
* '''Regulation:'''  
 
* '''Regulation:'''  
 +
** repressed by [[SinR]] [http://www.ncbi.nlm.nih.gov/sites/entrez/16923912 PubMed]
 
** repressed during exponential growth ([[ScoC]]) [http://www.ncbi.nlm.nih.gov/sites/entrez/16923912 PubMed]
 
** repressed during exponential growth ([[ScoC]]) [http://www.ncbi.nlm.nih.gov/sites/entrez/16923912 PubMed]
  
 
* '''Regulatory mechanism:''' activation by [[DegU]], not activated by [[DegU]]-P [http://www3.interscience.wiley.com/journal/122328658/abstract PubMed]
 
* '''Regulatory mechanism:''' activation by [[DegU]], not activated by [[DegU]]-P [http://www3.interscience.wiley.com/journal/122328658/abstract PubMed]
 +
** [[SinR]]: transcription repression [http://www.ncbi.nlm.nih.gov/sites/entrez/16923912 PubMed]
 
** [[ScoC]]: transcription repression [http://www.ncbi.nlm.nih.gov/sites/entrez/16923912 PubMed]
 
** [[ScoC]]: transcription repression [http://www.ncbi.nlm.nih.gov/sites/entrez/16923912 PubMed]
  

Revision as of 17:23, 11 June 2009

  • Description: minor extracellular serine protease, involved in control of swarming motility PubMed

Gene name epr
Synonyms ipa-15r
Essential no
Product minor extracellular serine protease
Function protein degradation
MW, pI 69 kDa, 9.875
Gene length, protein length 1935 bp, 645 aa
Immediate neighbours ywbA, sacX
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
Epr context.gif
This image was kindly provided by SubtiList



The gene

Basic information

  • Locus tag: BSU38400

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: peptidase S8 family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization: secreted (according to Swiss-Prot), extracellular (signal peptide) PubMed

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Monica Gupta, Kestur Krishnamurthy Rao
Epr plays a key role in DegU-mediated swarming motility of Bacillus subtilis.
FEMS Microbiol Lett: 2009, 295(2);187-94
[PubMed:19416356] [WorldCat.org] [DOI] (I p)

Birgit Voigt, Haike Antelmann, Dirk Albrecht, Armin Ehrenreich, Karl-Heinz Maurer, Stefan Evers, Gerhard Gottschalk, Jan Maarten van Dijl, Thomas Schweder, Michael Hecker
Cell physiology and protein secretion of Bacillus licheniformis compared to Bacillus subtilis.
J Mol Microbiol Biotechnol: 2009, 16(1-2);53-68
[PubMed:18957862] [WorldCat.org] [DOI] (I p)


  1. Author1, Author2 & Author3 (year) Title Journal volume: page-page. PubMed