SpoIIE

• Description: protein serine phosphatase, septum-associated PP2C, dephosphorylation of SpoIIAA
  
  

Gene name	spoIIE
Synonyms	spoIIH, spoIIK
Essential	no
Product	protein serine phosphatase, septum-associated PP2C
Function	control of SigF activity required for normal formation of the asymmetric septum
MW, pI	91 kDa, 6.137
Gene length, protein length	2481 bp, 827 aa
Immediate neighbours	trnSL-Glu1, yabS
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList

The gene

Basic information

• Locus tag:

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity: A phosphoprotein + H₂O = a protein + phosphate (according to Swiss-Prot) dephosphorylation of SpoIIAA

• Protein family: PP2C phosphatase

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions: SpoIIE-FtsZ, SpoIIE-SpoIIAB, SpoIIE-SpoIIE, SpoIIQ-SpoIIE

• Localization: cell membrane (according to Swiss-Prot)

Database entries

• Structure:

• Swiss prot entry: P37475

• KEGG entry: BSU00640

• E.C. number: 3.1.3.16

Expression and regulation

• Operon:

• Sigma factor:

• Regulation:

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

Labs working on this gene/protein

Imrich Barak, Slovak Academy of Science, Bratislava, Slovakia homepage

References

1. Author1, Author2 & Author3 (year) Title Journal volume: page-page. PubMed