Difference between revisions of "TopB"

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* '''Description:''' write here <br/><br/>
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* '''Description:''' DNA topoisomerase III <br/><br/>
  
 
{| align="right" border="1" cellpadding="2"  
 
{| align="right" border="1" cellpadding="2"  
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|style="background:#ABCDEF;" align="center"| '''Essential''' || no  
 
|style="background:#ABCDEF;" align="center"| '''Essential''' || no  
 
|-
 
|-
|style="background:#ABCDEF;" align="center"| '''Product''' || DNA topoisomerase III (EC 5.99.1.2)
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|style="background:#ABCDEF;" align="center"| '''Product''' || DNA topoisomerase III
 
|-
 
|-
|style="background:#ABCDEF;" align="center"|'''Function''' ||  
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|style="background:#ABCDEF;" align="center"|'''Function''' || replication
 
|-
 
|-
 
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 81 kDa, 9.879   
 
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 81 kDa, 9.879   

Revision as of 11:53, 7 April 2009

  • Description: DNA topoisomerase III

Gene name topB
Synonyms
Essential no
Product DNA topoisomerase III
Function replication
MW, pI 81 kDa, 9.879
Gene length, protein length 2181 bp, 727 aa
Immediate neighbours lrpC, ydaJ
Gene sequence (+200bp) Protein sequence
Genetic context
TopB context.gif
This image was kindly provided by SubtiList



The gene

Basic information

  • Coordinates:

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family:
  • Paralogous protein(s): TopA, one of the two proteins has to be present for viability PubMed

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization:

Database entries

  • Structure:
  • Swiss prot entry:
  • KEGG entry: [2]
  • E.C. number:

Additional information

Expression and regulation

  • Operon:
  • Sigma factor:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

  1. Thomaides, H. B., Davison, E. J., Burston, L., Johnson, H., Brown, D. R., Hunt, A. C., Errington, J., and Czaplewski, L. (2007) Essential bacterial functions encoded by gene pairs. J Bacteriol 189, 591-602. PubMed
  2. Author1, Author2 & Author3 (year) Title Journal volume: page-page. PubMed