Difference between revisions of "YpqP"

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* '''Description:''' similar to capsular polysaccharide biosynthesis, in ''B. subtilis'' 168 the gene is disrupted by the [[SP-beta prophage]] <br/><br/>
+
* '''Description:''' C-terminal part of the split gene ''spsM'' (together with ''[[yodU]]''), spore envelope polysaccharide biosynthesis, in ''B. subtilis'' 168 the gene is disrupted by the [[SP-beta prophage]] <br/><br/>
  
 
{| align="right" border="1" cellpadding="2"  
 
{| align="right" border="1" cellpadding="2"  
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|style="background:#ABCDEF;" align="center"| '''Product''' || unknown  
 
|style="background:#ABCDEF;" align="center"| '''Product''' || unknown  
 
|-
 
|-
|style="background:#ABCDEF;" align="center"|'''Function''' || unknown
+
|style="background:#ABCDEF;" align="center"|'''Function''' || spore envelope polysaccharide biosynthesis
 
|-
 
|-
 
|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU21670 ypqP]
 
|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU21670 ypqP]
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|style="background:#ABCDEF;" align="center"| '''MW, pI''' ||  - , -   
 
|style="background:#ABCDEF;" align="center"| '''MW, pI''' ||  - , -   
 
|-
 
|-
|style="background:#ABCDEF;" align="center"| '''Gene length, protein length''' || 606 bp, -
+
|style="background:#ABCDEF;" align="center"| '''Gene length, protein length''' || 606 bp, SpsM: 341 aa
 
|-
 
|-
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[sprA]]'', ''[[msrB]]''
+
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[yokA]]'', ''[[msrB]]''
 
|-
 
|-
 
|style="background:#FAF8CC;" align="center"|'''[http://subtiwiki.uni-goettingen.de/ypqP_nucleotide.txt    Gene sequence      (+200bp)  ]'''  
 
|style="background:#FAF8CC;" align="center"|'''[http://subtiwiki.uni-goettingen.de/ypqP_nucleotide.txt    Gene sequence      (+200bp)  ]'''  
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= [[Categories]] containing this gene/protein =
 
= [[Categories]] containing this gene/protein =
{{SubtiWiki category|[[capsule biosynthesis and degradation]]}},
 
 
{{SubtiWiki category|[[membrane proteins]]}},
 
{{SubtiWiki category|[[membrane proteins]]}},
 
{{SubtiWiki category|[[sporulation proteins]]}}
 
{{SubtiWiki category|[[sporulation proteins]]}}
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=== Additional information===
 
=== Additional information===
 
+
* rearrangement (deletion of the [[SP-beta prophage]] and generation of the spsM gene) occurs during [[sporulation]] to allow production of spore polysaccharide {{PubMed|25299644}}
 
 
  
  
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* '''Protein family:'''
 
* '''Protein family:'''
  
* '''Paralogous protein(s):'''
+
* '''Paralogous protein(s):''' [[EpsC]] (for SpsM)
  
 
=== Extended information on the protein ===
 
=== Extended information on the protein ===
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* '''Kinetic information:'''
 
* '''Kinetic information:'''
  
* '''Domains:'''  
+
* '''Domains:''' SpsM: Polysacc_synt_2 domain (Pfam accession number, PF02719) in the 18–296-aa region {{PubMed|25299644}}
  
 
* '''Modification:'''
 
* '''Modification:'''

Revision as of 08:20, 10 October 2014

  • Description: C-terminal part of the split gene spsM (together with yodU), spore envelope polysaccharide biosynthesis, in B. subtilis 168 the gene is disrupted by the SP-beta prophage

Gene name ypqP
Synonyms
Essential no
Product unknown
Function spore envelope polysaccharide biosynthesis
Gene expression levels in SubtiExpress: ypqP
MW, pI - , -
Gene length, protein length 606 bp, SpsM: 341 aa
Immediate neighbours yokA, msrB
Gene sequence (+200bp) Protein sequence
Genetic context
YpqP context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
YpqP expression.png















Categories containing this gene/protein

membrane proteins, sporulation proteins

This gene is a member of the following regulons

The gene

Basic information

  • Locus tag: BSU21670

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information


The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family:
  • Paralogous protein(s): EpsC (for SpsM)

Extended information on the protein

  • Kinetic information:
  • Domains: SpsM: Polysacc_synt_2 domain (Pfam accession number, PF02719) in the 18–296-aa region PubMed
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Operon: ypqP (accoriding to DBTBS)
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References