Difference between revisions of "SpoIIE"

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{{SubtiWiki category|[[sigma factors and their control]]}},
 
{{SubtiWiki category|[[sigma factors and their control]]}},
 
{{SubtiWiki category|[[membrane proteins]]}},
 
{{SubtiWiki category|[[membrane proteins]]}},
{{SubtiWiki category|[[sporulation/ other]]}}
+
{{SubtiWiki category|[[Sporulation#Sporulation_proteins/_other|sporulation proteins]]}}
  
 
= This gene is a member of the following [[regulons]] =
 
= This gene is a member of the following [[regulons]] =

Revision as of 11:09, 24 April 2014

Gene name spoIIE
Synonyms spoIIH, spoIIK
Essential no
Product protein serine phosphatase, septum-associated PP2C
Function control of SigF activity
required for normal formation of the asymmetric septum
Gene expression levels in SubtiExpress: spoIIE
Interactions involving this protein in SubtInteract: SpoIIE
Metabolic function and regulation of this protein in SubtiPathways:
spoIIE
MW, pI 91 kDa, 6.137
Gene length, protein length 2481 bp, 827 aa
Immediate neighbours trnSL-Glu1, yabS
Sequences Protein DNA DNA_with_flanks
Genetic context
SpoIIE context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
SpoIIE expression.png















Categories containing this gene/protein

protein modification, sigma factors and their control, membrane proteins, sporulation proteins

This gene is a member of the following regulons

Spo0A regulon

The gene

Basic information

  • Locus tag: BSU00640

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: dephosphorylation of SpoIIAA
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Localization:
    • cell membrane (according to Swiss-Prot)
    • localizes to the polar cell division sites where it causes FtsZ to relocate from mid-cell to form polar Z-rings

Database entries

  • KEGG entry: [3]

Additional information

Expression and regulation

  • Operon: spoIIE (DBTBS)
  • Regulation:
    • expressed under conditions that trigger sporulation (Spo0A) PubMed
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Imrich Barak, Slovak Academy of Science, Bratislava, Slovakia homepage

Your additional remarks

References

Modeling of SigF activation


Original Publications