YkwC

• Description: putative beta-hydroxyacid dehydrogenase
  
  

Gene name	ykwC
Synonyms
Essential	no
Product	putative beta-hydroxyacid dehydrogenase
Function	unknown
Gene expression levels in SubtiExpress: ykwC
MW, pI	30 kDa, 5.109
Gene length, protein length	864 bp, 288 aa
Immediate neighbours	mcpC, ykwD
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

poorly characterized/ putative enzymes, most abundant proteins

The gene

Basic information

• Locus tag: BSU13960

Database entries

• BsubCyc: BSU13960

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family: 3-hydroxyisobutyrate dehydrogenase family (according to Swiss-Prot)

• Paralogous protein(s): YfjR

Extended information on the protein

• Kinetic information:

• Domains:

• Modification: phosphorylated on Ser-281 by PrkC, dephosphorylated by PrpC, phosphorylation abolishes the oxidoreductase activity of YkwC in vitro and in vivo PubMed

• Cofactors:

• Effectors of protein activity:

• Interactions:

• Localization:

Database entries

• BsubCyc: BSU13960

• Structure:

• UniProt: O34948

• KEGG entry: [2]

• E.C. number:

Expression and regulation

• Operon:

• Expression browser: ykwC PubMed

• Sigma factor:

• Regulation:

• Regulatory mechanism:

• Additional information:
  • belongs to the 100 most abundant proteins PubMed
  • number of protein molecules per cell (minimal medium with glucose and ammonium): 7715 PubMed
  • number of protein molecules per cell (complex medium with amino acids, without glucose): 3613 PubMed

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody: