Difference between revisions of "AppC"

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* '''Kinetic information:'''
 
* '''Kinetic information:'''
  
* '''Domains:'''  
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* '''[[Domains]]:'''  
  
 
* '''Modification:'''
 
* '''Modification:'''
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* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=appC_1216210_1217121_1 appC] {{PubMed|22383849}}
 
* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=appC_1216210_1217121_1 appC] {{PubMed|22383849}}
  
* '''Sigma factor:'''  
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* '''[[Sigma factor]]:'''  
  
 
* '''Regulation:'''  
 
* '''Regulation:'''  
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* '''Mutant:'''
 
* '''Mutant:'''
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** GP2100 (D(''[[appD]]-[[appF]]-[[appA]]-[[appB]]-[[appC]]'')::''spc''), available in [[Jörg Stülke]]'s lab
  
 
* '''Expression vector:'''
 
* '''Expression vector:'''

Revision as of 08:52, 20 July 2015

Gene name appC
Synonyms
Essential no
Product oligopeptide ABC transporter (permease))
Function uptake of oligopeptides
Gene expression levels in SubtiExpress: appC
Interactions involving this protein in SubtInteract: AppC
Metabolic function and regulation of this protein in SubtiPathways:
appC
MW, pI 33 kDa, 9.777
Gene length, protein length 909 bp, 303 aa
Immediate neighbours appB, yjbA
Sequences Protein DNA DNA_with_flanks
Genetic context
AppC context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
AppC expression.png















Categories containing this gene/protein

ABC transporters, utilization of nitrogen sources other than amino acids, membrane proteins

This gene is a member of the following regulons

CodY regulon, ScoC regulon

The gene

Basic information

  • Locus tag: BSU11400

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: ABC transmembrane type-1 domain (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
    • repressed during exponential growth (ScoC) PubMed
    • repressed during growth in the presence of branched chain amino acids (CodY) PubMed
  • Additional information:

Biological materials

  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References