Difference between revisions of "Main Page"

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<big>'''Paper of the month: March 2014'''</big>  
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<big>'''Paper of the month: April 2014'''</big>  
 
* In a paper from the labs of [[Roberto Kolter]] and [[Richard Losick]] {{PubMed|22541437}} it was reported that ''B. subtilis'' synthesizes norspermidine and that this compound is involved in biofilm disassembly. Now, [http://www.ncbi.nlm.nih.gov/pubmed/24529384 Hobley et al.] from the lab of [[Nicola Stanley-Wall]] provide compelling evidence that ''B. subtilis'' does not produce norspermidine, that previous function annotations of a norspermidine biosynthetic pathway were made in error, and that norspermidine stimulates [[biofilm formation]].
 
* In a paper from the labs of [[Roberto Kolter]] and [[Richard Losick]] {{PubMed|22541437}} it was reported that ''B. subtilis'' synthesizes norspermidine and that this compound is involved in biofilm disassembly. Now, [http://www.ncbi.nlm.nih.gov/pubmed/24529384 Hobley et al.] from the lab of [[Nicola Stanley-Wall]] provide compelling evidence that ''B. subtilis'' does not produce norspermidine, that previous function annotations of a norspermidine biosynthetic pathway were made in error, and that norspermidine stimulates [[biofilm formation]].
* '''Relevant ''Subti''Wiki pages:''' [[Nicola Stanley-Wall]], [[biofilm formation]], [[YaaO]], [[GabT]]
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* '''Relevant ''Subti''Wiki pages:''' [[Mark Dillingham]], [[DNA repair/ recombination]], [[AddA]], [[AddB]]
<pubmed> 24529384 </pubmed>
+
<pubmed> 24682829 24670664 </pubmed>
* See a comment on this issue:
 
<pubmed> 24608334 </pubmed>
 
 
* [[Previous papers of the month]]
 
* [[Previous papers of the month]]
  

Revision as of 10:58, 2 April 2014

Welcome to SubtiWiki! - Bacillus subtilis annotation the "wiki" way!

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Now online: A new description of SubtiWiki and its acompanying modules in the 2014 Database issue of Nucleic Acids Research



Paper of the month: April 2014

Neville S Gilhooly, Mark S Dillingham
Recombination hotspots attenuate the coupled ATPase and translocase activities of an AddAB-type helicase-nuclease.
Nucleic Acids Res: 2014, 42(9);5633-43
[PubMed:24682829] [WorldCat.org] [DOI] (I p)

Wojciech W Krajewski, Xin Fu, Martin Wilkinson, Nora B Cronin, Mark S Dillingham, Dale B Wigley
Structural basis for translocation by AddAB helicase-nuclease and its arrest at χ sites.
Nature: 2014, 508(7496);416-9
[PubMed:24670664] [WorldCat.org] [DOI] (I p)


New procedure for account creation:

  • Due to massive spam attacks, we had to change our policy for the creation of accounts. If you want to create an account, just send me a mail. We will create the account for you as quickly as possible, then you can change your password. This does not affect existing accounts, which remain active.
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News in SubtiWiki:

  • April 2013: SubtiWiki uses a new, faster Mediawiki platform! The times for page access are significantly reduced. Enjoy!
  • March 2013: updated Excel files that map all genes to categories and regulons as well as the general updated identity mapping of all genes were uploaded.
  • October 2012: the essential genes have been categorized
  • September 2012: 300 mutant strains available at the BGSC were added to the corresponding gene pages
  • August 2012: SubtiExpress, the new compagnon of SubtiWiki devoted to gene expression is online! Try it out!
  • April 2012: Links for expression data under 104 different conditions (based on Nicolas et al., 2012) have been added to the expression section of the individual gene pages
  • April 2011: SubtInteract, a presentation of protein-protein interactions in B. subtilis, is online!
  • December 2010: SubtiCellPublisher allows the conversion of CellDesigner diagrams to navigatable presentations in the style of SubtiPathways



Genes (examples) Additional pages
spo0A SubtiPathways
glnA SubtInteract
rny SubtiExpress
psdA Regulons
pckA methods
dnaA metabolism
rnpA categories
sigB genome-wide analyses
ptkA list of plasmids
mreC labs working on Bacillus
ccpA the people behind SubtiWiki
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Publications describing SubtiWiki and SubtiPathways: