Difference between revisions of "AhpF"

From SubtiWiki
Jump to: navigation, search
Line 60: Line 60:
  
 
=== Database entries ===
 
=== Database entries ===
 +
* '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU40100&redirect=T BSU40100]
  
 
* '''DBTBS entry:''' [http://dbtbs.hgc.jp/COG/prom/ahpCF.html]
 
* '''DBTBS entry:''' [http://dbtbs.hgc.jp/COG/prom/ahpCF.html]
Line 99: Line 100:
  
 
=== Database entries ===
 
=== Database entries ===
 +
* '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU40100&redirect=T BSU40100]
  
 
* '''Structure:''' [http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1HYU 1HYU] (from ''Salmonella typhimurium'', 52% identity, 69% similarity) {{PubMed|11300769}}
 
* '''Structure:''' [http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1HYU 1HYU] (from ''Salmonella typhimurium'', 52% identity, 69% similarity) {{PubMed|11300769}}

Revision as of 15:15, 2 April 2014

  • Description: alkyl hydroperoxide reductase (large subunit) / NADH dehydrogenase

Gene name ahpF
Synonyms ndh
Essential no
Product alkyl hydroperoxide reductase (large subunit) /
NADH dehydrogenase
Function resistance against peroxide stres
Gene expression levels in SubtiExpress: ahpF
Metabolic function and regulation of this protein in SubtiPathways:
ahpF
MW, pI 54 kDa, 4.705
Gene length, protein length 1527 bp, 509 aa
Immediate neighbours ahpC, bglA
Sequences Protein DNA DNA_with_flanks
Genetic context
AhpF context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
AhpF expression.png




























Categories containing this gene/protein

resistance against oxidative and electrophile stress, membrane proteins, phosphoproteins

This gene is a member of the following regulons

PerR regulon

The gene

Basic information

  • Locus tag: BSU40100

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: NADH + acceptor = NAD+ + reduced acceptor (according to Swiss-Prot)
  • Protein family: class-II pyridine nucleotide-disulfide oxidoreductase family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
    • phosphorylation on (Ser-48 OR Ser-49) PubMed
    • phosphorylated on Arg-457 PubMed
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure: 1HYU (from Salmonella typhimurium, 52% identity, 69% similarity) PubMed
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References