Difference between revisions of "YhfU"
| Line 42: | Line 42: | ||
= This gene is a member of the following [[regulons]] = | = This gene is a member of the following [[regulons]] = | ||
| − | + | {{SubtiWiki regulon|[[BirA regulon]]}} | |
=The gene= | =The gene= | ||
| Line 111: | Line 111: | ||
* '''Regulation:''' | * '''Regulation:''' | ||
| + | ** repressed in the presence of biotin ([[BirA]]) {{PubMed|11717296}} | ||
* '''Regulatory mechanism:''' | * '''Regulatory mechanism:''' | ||
| + | ** [[BirA]]: transcription repression {{PubMed|11717296}} | ||
* '''Additional information:''' | * '''Additional information:''' | ||
| Line 138: | Line 140: | ||
<pubmed>21437340, 20497229, </pubmed> | <pubmed>21437340, 20497229, </pubmed> | ||
== Original publications == | == Original publications == | ||
| − | <pubmed>18763711, 17301237 </pubmed> | + | <pubmed>18763711, 17301237 11717296</pubmed> |
[[Category:Protein-coding genes]] | [[Category:Protein-coding genes]] | ||
Revision as of 19:13, 13 July 2013
- Description: S protein of biotin ECF transporter
| Gene name | yhfU |
| Synonyms | bioY |
| Essential | no |
| Product | S protein of biotin ECF transporter |
| Function | uptake of biotin |
| Gene expression levels in SubtiExpress: yhfU | |
| MW, pI | 19 kDa, 10.681 |
| Gene length, protein length | 558 bp, 186 aa |
| Immediate neighbours | yhfT, hemAT |
| Sequences | Protein DNA DNA_with_flanks |
Genetic context 
This image was kindly provided by SubtiList
| |
Expression at a glance PubMed
| |
Contents
Categories containing this gene/protein
ECF transporter, biosynthesis of cofactors, membrane proteins
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU10370
Phenotypes of a mutant
Database entries
- DBTBS entry: no entry
- SubtiList entry: [1]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: uptake of biotin PubMed
- Protein family: bioY family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Localization:
- membrane associated PubMed
Database entries
- Structure:
- UniProt: O07620
- KEGG entry: [2]
- E.C. number:
Additional information
Expression and regulation
- Operon:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Reviews
Steven Lin, John E Cronan
Closing in on complete pathways of biotin biosynthesis.
Mol Biosyst: 2011, 7(6);1811-21
[PubMed:21437340]
[WorldCat.org]
[DOI]
(I p)
Thomas Eitinger, Dmitry A Rodionov, Mathias Grote, Erwin Schneider
Canonical and ECF-type ATP-binding cassette importers in prokaryotes: diversity in modular organization and cellular functions.
FEMS Microbiol Rev: 2011, 35(1);3-67
[PubMed:20497229]
[WorldCat.org]
[DOI]
(I p)
Original publications
Hannes Hahne, Susanne Wolff, Michael Hecker, Dörte Becher
From complementarity to comprehensiveness--targeting the membrane proteome of growing Bacillus subtilis by divergent approaches.
Proteomics: 2008, 8(19);4123-36
[PubMed:18763711]
[WorldCat.org]
[DOI]
(I p)
Peter Hebbeln, Dmitry A Rodionov, Anja Alfandega, Thomas Eitinger
Biotin uptake in prokaryotes by solute transporters with an optional ATP-binding cassette-containing module.
Proc Natl Acad Sci U S A: 2007, 104(8);2909-14
[PubMed:17301237]
[WorldCat.org]
[DOI]
(P p)
J M Lee, S Zhang, S Saha, S Santa Anna, C Jiang, J Perkins
RNA expression analysis using an antisense Bacillus subtilis genome array.
J Bacteriol: 2001, 183(24);7371-80
[PubMed:11717296]
[WorldCat.org]
[DOI]
(P p)
