Difference between revisions of "PdxS"

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|style="background:#ABCDEF;" align="center"| '''Product''' || synthase domain of pyridoxal-5'-phosphate synthase
 
|style="background:#ABCDEF;" align="center"| '''Product''' || synthase domain of pyridoxal-5'-phosphate synthase
 
|-
 
|-
|style="background:#ABCDEF;" align="center"|'''Function''' || unknown
+
|style="background:#ABCDEF;" align="center"|'''Function''' || vitamin B6 synthesis
 
|-
 
|-
 
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 31 kDa, 5.085   
 
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 31 kDa, 5.085   

Revision as of 10:23, 23 February 2009

  • Description: subunit of pyridoxal-5'-phosphate synthase

Gene name pdxS
Synonyms yaaD
Essential no
Product synthase domain of pyridoxal-5'-phosphate synthase
Function vitamin B6 synthesis
MW, pI 31 kDa, 5.085
Gene length, protein length 882 bp, 294 aa
Immediate neighbours dacA, pdxT
Gene sequence (+200bp) Protein sequence
Genetic context
YaaD context.gif



The gene

Basic information

  • Coordinates:

Phenotypes of a mutant

auxotrophic for pyridoxal 5'-phosphate PubMed

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification: phosphorylated on STY PubMed
  • Cofactor(s):
  • Effectors of protein activity:
  • Localization:

Database entries

  • Swiss prot entry:
  • KEGG entry:
  • E.C. number:

Additional information

Expression and regulation

  • Sigma factor:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

  1. Molle et al. (2003) The Spo0A regulon of Bacillus subtilis.Mol. Microbiol. 50: 1683-1701. PubMed
  2. Raschle et al. (2005) On the two components of pyridoxal 5'-phosphate synthase from Bacillus subtilis.J. Biol. Chem. 280: 32291-32300. PubMed
  3. Belitsky (2004) Physical and enzymological interaction of Bacillus subtilis proteins required for de novo pyridoxal 5'-phosphate biosynthesis.J. Bacteriol. 186: 1191-1196. PubMed
  4. Levine et al. (2006) Analysis of the dynamic Bacillus subtilis Ser/Thr/Tyr phosphoproteome implicated in a wide variety of celular processes. Proteomics 6, 2157-2173. PubMed