Difference between revisions of "QcrC"

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* '''[[SubtInteract|Interactions]]:'''
 
* '''[[SubtInteract|Interactions]]:'''
 
** [[KinB]]-[[QcrC]]  {{PubMed|23599347}}
 
** [[KinB]]-[[QcrC]]  {{PubMed|23599347}}
 +
** part of a [[Respiratory complexes and supercomplexes|respiratory supercomplex]] {{PubMed|23880299}}
 +
** [[QcrA]]-[[QcrB]]-[[QcrC]] {{PubMed|23880299}}
  
* '''[[Localization]]:''' cell membrane (according to Swiss-Prot)
+
* '''[[Localization]]:'''  
 +
** cell membrane {{PubMed|23880299}}
  
 
=== Database entries ===
 
=== Database entries ===
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=References=
 
=References=
<pubmed>8631715,7592464,12850135 ,12107147,23599347 20817675</pubmed>
+
<pubmed>8631715,7592464,12850135 ,12107147,23599347 20817675 23880299</pubmed>
  
 
[[Category:Protein-coding genes]]
 
[[Category:Protein-coding genes]]

Revision as of 18:07, 11 August 2013

  • Description: menaquinol:cytochrome c oxidoreductase (cytochrome b/c subunit), component of the cytochrome bc complex

Gene name qcrC
Synonyms bfcC, petD
Essential no
Product menaquinol:cytochrome c oxidoreductase (cytochrome b/c subunit)
Function respiration
Gene expression levels in SubtiExpress: qcrC
Interactions involving this protein in SubtInteract: QcrC
MW, pI 28 kDa, 7.171
Gene length, protein length 765 bp, 255 aa
Immediate neighbours ypjA, qcrB
Sequences Protein DNA DNA_with_flanks
Genetic context
QcrC context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
QcrC expression.png















Categories containing this gene/protein

respiration, membrane proteins

This gene is a member of the following regulons

AbrB regulon, ResD regulon

The gene

Basic information

  • Locus tag: BSU22540

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Pedro M F Sousa, Marco A M Videira, Filipe A S Santos, Brian L Hood, Thomas P Conrads, Ana M P Melo
The bc:caa3 supercomplexes from the Gram positive bacterium Bacillus subtilis respiratory chain: a megacomplex organization?
Arch Biochem Biophys: 2013, 537(1);153-60
[PubMed:23880299] [WorldCat.org] [DOI] (I p)

Ilana Kolodkin-Gal, Alexander K W Elsholz, Christine Muth, Peter R Girguis, Roberto Kolter, Richard Losick
Respiration control of multicellularity in Bacillus subtilis by a complex of the cytochrome chain with a membrane-embedded histidine kinase.
Genes Dev: 2013, 27(8);887-99
[PubMed:23599347] [WorldCat.org] [DOI] (I p)

Onuma Chumsakul, Hiroki Takahashi, Taku Oshima, Takahiro Hishimoto, Shigehiko Kanaya, Naotake Ogasawara, Shu Ishikawa
Genome-wide binding profiles of the Bacillus subtilis transition state regulator AbrB and its homolog Abh reveals their interactive role in transcriptional regulation.
Nucleic Acids Res: 2011, 39(2);414-28
[PubMed:20817675] [WorldCat.org] [DOI] (I p)

Hans-Matti Blencke, Georg Homuth, Holger Ludwig, Ulrike Mäder, Michael Hecker, Jörg Stülke
Transcriptional profiling of gene expression in response to glucose in Bacillus subtilis: regulation of the central metabolic pathways.
Metab Eng: 2003, 5(2);133-49
[PubMed:12850135] [WorldCat.org] [DOI] (P p)

Ulrike Mäder, Georg Homuth, Christian Scharf, Knut Büttner, Rüdiger Bode, Michael Hecker
Transcriptome and proteome analysis of Bacillus subtilis gene expression modulated by amino acid availability.
J Bacteriol: 2002, 184(15);4288-95
[PubMed:12107147] [WorldCat.org] [DOI] (P p)

G Sun, E Sharkova, R Chesnut, S Birkey, M F Duggan, A Sorokin, P Pujic, S D Ehrlich, F M Hulett
Regulators of aerobic and anaerobic respiration in Bacillus subtilis.
J Bacteriol: 1996, 178(5);1374-85
[PubMed:8631715] [WorldCat.org] [DOI] (P p)

J Yu, L Hederstedt, P J Piggot
The cytochrome bc complex (menaquinone:cytochrome c reductase) in Bacillus subtilis has a nontraditional subunit organization.
J Bacteriol: 1995, 177(23);6751-60
[PubMed:7592464] [WorldCat.org] [DOI] (P p)