Difference between revisions of "CotT"
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= This gene is a member of the following [[regulons]] = | = This gene is a member of the following [[regulons]] = | ||
| − | {{SubtiWiki regulon|[[SigK regulon]]}} | + | {{SubtiWiki regulon|[[SigK regulon]]}}, |
| + | {{SubtiWiki regulon|[[GerE regulon]]}}, | ||
| + | {{SubtiWiki regulon|[[SigE regulon]]}}, | ||
| + | {{SubtiWiki regulon|[[SpoIIID regulon]]}} | ||
| + | |||
=The gene= | =The gene= | ||
| Line 92: | Line 92: | ||
* '''[[Localization]]:''' | * '''[[Localization]]:''' | ||
| − | ** inner spore coat {{PubMed|19933362}} | + | ** inner spore coat, localization depends on [[SafA]] {{PubMed|22171814,19933362}} |
=== Database entries === | === Database entries === | ||
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* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=cotT_1280626_1280949_-1 cotT] {{PubMed|22383849}} | * '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=cotT_1280626_1280949_-1 cotT] {{PubMed|22383849}} | ||
| − | * '''Sigma factor:''' [[SigK]] {{PubMed|2546006,15699190,15383836}} | + | * '''[[Sigma factor]]:''' [[SigK]] {{PubMed|2546006,15699190,15383836}}, [[SigE]] {{PubMed|15383836}} |
* '''Regulation:''' | * '''Regulation:''' | ||
| − | ** expressed | + | ** expressed during sporulation in the mother cell ([[SigE]], [SigK]], [[GerE]], [[SpoIIID]]) {{PubMed|2546006,15699190,15383836}} |
* '''Regulatory mechanism:''' | * '''Regulatory mechanism:''' | ||
** [[SpoIIID]]: transcription activation {{PubMed|15383836}} | ** [[SpoIIID]]: transcription activation {{PubMed|15383836}} | ||
| + | ** [[GerE]]: transcription repression {{PubMed|15383836}} | ||
* '''Additional information:''' | * '''Additional information:''' | ||
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=References= | =References= | ||
| − | <pubmed>10714992,1917883,2546006,15699190, 15383836 19933362 </pubmed> | + | <pubmed>10714992,1917883,2546006,15699190, 15383836 19933362 22171814 </pubmed> |
[[Category:Protein-coding genes]] | [[Category:Protein-coding genes]] | ||
Revision as of 16:06, 13 August 2013
- Description: spore coat protein (inner)
| Gene name | cotT |
| Synonyms | |
| Essential | no |
| Product | spore coat protein (inner) |
| Function | resistance of the spore |
| Gene expression levels in SubtiExpress: cotT | |
| MW, pI | 12 kDa, 9.466 |
| Gene length, protein length | 321 bp, 107 aa |
| Immediate neighbours | ctaO, pdaC |
| Sequences | Protein DNA DNA_with_flanks |
Genetic context 
This image was kindly provided by SubtiList
| |
Expression at a glance PubMed
| |
Contents
Categories containing this gene/protein
This gene is a member of the following regulons
SigK regulon, GerE regulon, SigE regulon, SpoIIID regulon
The gene
Basic information
- Locus tag: BSU12090
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family:
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
Database entries
- Structure:
- UniProt: P11863
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Operon: cotT PubMed
- Regulatory mechanism:
- Additional information:
Biological materials
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Arthur Aronson, Purdue University, West Lafayette, USA homepage
Your additional remarks
References
Peter T McKenney, Patrick Eichenberger
Dynamics of spore coat morphogenesis in Bacillus subtilis.
Mol Microbiol: 2012, 83(2);245-60
[PubMed:22171814]
[WorldCat.org]
[DOI]
(I p)
Daisuke Imamura, Ritsuko Kuwana, Hiromu Takamatsu, Kazuhito Watabe
Localization of proteins to different layers and regions of Bacillus subtilis spore coats.
J Bacteriol: 2010, 192(2);518-24
[PubMed:19933362]
[WorldCat.org]
[DOI]
(I p)
Leif Steil, Mónica Serrano, Adriano O Henriques, Uwe Völker
Genome-wide analysis of temporally regulated and compartment-specific gene expression in sporulating cells of Bacillus subtilis.
Microbiology (Reading): 2005, 151(Pt 2);399-420
[PubMed:15699190]
[WorldCat.org]
[DOI]
(P p)
Patrick Eichenberger, Masaya Fujita, Shane T Jensen, Erin M Conlon, David Z Rudner, Stephanie T Wang, Caitlin Ferguson, Koki Haga, Tsutomu Sato, Jun S Liu, Richard Losick
The program of gene transcription for a single differentiating cell type during sporulation in Bacillus subtilis.
PLoS Biol: 2004, 2(10);e328
[PubMed:15383836]
[WorldCat.org]
[DOI]
(I p)
H Takamatsu, T Kodama, A Imamura, K Asai, K Kobayashi, T Nakayama, N Ogasawara, K Watabe
The Bacillus subtilis yabG gene is transcribed by SigK RNA polymerase during sporulation, and yabG mutant spores have altered coat protein composition.
J Bacteriol: 2000, 182(7);1883-8
[PubMed:10714992]
[WorldCat.org]
[DOI]
(P p)
N Bourne, P C FitzJames, A I Aronson
Structural and germination defects of Bacillus subtilis spores with altered contents of a spore coat protein.
J Bacteriol: 1991, 173(20);6618-25
[PubMed:1917883]
[WorldCat.org]
[DOI]
(P p)
A I Aronson, H Y Song, N Bourne
Gene structure and precursor processing of a novel Bacillus subtilis spore coat protein.
Mol Microbiol: 1989, 3(3);437-44
[PubMed:2546006]
[WorldCat.org]
[DOI]
(P p)
