Difference between revisions of "HemN"
| Line 29: | Line 29: | ||
<div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div> | <div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div> | ||
|- | |- | ||
| − | |colspan="2" |'''[http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=hemN_2629718_2630857_-1 Expression at a glance]'''   {{PubMed|22383849}}<br/>[[Image:hemN_expression.png|500px]] | + | |colspan="2" |'''[http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=hemN_2629718_2630857_-1 Expression at a glance]'''   {{PubMed|22383849}}<br/>[[Image:hemN_expression.png|500px|link=http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU25500]] |
|- | |- | ||
|} | |} | ||
Revision as of 13:58, 16 May 2013
- Description: anaerobic coproporphyrinogen III oxidase
| Gene name | hemN |
| Synonyms | yqeR |
| Essential | no |
| Product | anaerobic coproporphyrinogen III oxidase |
| Function | heme biosynthesis |
| Gene expression levels in SubtiExpress: hemN | |
| MW, pI | 41 kDa, 5.534 |
| Gene length, protein length | 1098 bp, 366 aa |
| Immediate neighbours | hrcA, lepA |
| Sequences | Protein DNA DNA_with_flanks |
Genetic context 
This image was kindly provided by SubtiList
| |
Expression at a glance PubMed
| |
Contents
Categories containing this gene/protein
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU25500
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: Coproporphyrinogen-III + 2 S-adenosyl-L-methionine = protoporphyrinogen-IX + 2 CO2 + 2 L-methionine + 2 5'-deoxyadenosine (according to Swiss-Prot)
- Protein family: anaerobic coproporphyrinogen III oxidase family (according to Swiss-Prot)
- Paralogous protein(s): HemZ
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
Database entries
- Structure:
- UniProt: P54304
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Regulation:
- Regulatory mechanism:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
G Homuth, A Rompf, W Schumann, D Jahn
Transcriptional control of Bacillus subtilis hemN and hemZ.
J Bacteriol: 1999, 181(19);5922-9
[PubMed:10498703]
[WorldCat.org]
[DOI]
(P p)
B Hippler, G Homuth, T Hoffmann, C Hungerer, W Schumann, D Jahn
Characterization of Bacillus subtilis hemN.
J Bacteriol: 1997, 179(22);7181-5
[PubMed:9371469]
[WorldCat.org]
[DOI]
(P p)
G Homuth, M Heinemann, U Zuber, W Schumann
The genes of lepA and hemN form a bicistronic operon in Bacillus subtilis.
Microbiology (Reading): 1996, 142 ( Pt 7);1641-9
[PubMed:8757728]
[WorldCat.org]
[DOI]
(P p)
