GmuB

• Description: glucomannan-specific phosphotransferase system, EIIB component of the PTS
  
  

Gene name	gmuB
Synonyms	ydhM
Essential	no
Product	glucomannan-specific phosphotransferase system EIIB component
Function	glucomannan uptake and phosphorylation
Gene expression levels in SubtiExpress: gmuB
Interactions involving this protein in SubtInteract: GmuB
Metabolic function and regulation of this protein in SubtiPathways: Sugar catabolism
MW, pI	11 kDa, 4.724
Gene length, protein length	309 bp, 103 aa
Immediate neighbours	pbuE, gmuA
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

phosphotransferase systems, utilization of specific carbon sources, phosphoproteins

This gene is a member of the following regulons

AbrB regulon, CcpA regulon, GmuR regulon

The gene

Basic information

• Locus tag: BSU05810

Database entries

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family: PTS permease, lactose permease (Lac) family PubMed

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:
  • GmuA-GmuB, GmuB-GmuC

• Localization:

Database entries

• Structure:

• UniProt: O05505

• KEGG entry: [2]

• E.C. number:

Expression and regulation

• Operon: gmuB-gmuA-gmuC-gmuD-gmuR-gmuE-gmuF-gmuG PubMed

• Expression browser: gmuB PubMed

• Sigma factor: SigA PubMed

• Regulation:
  • induced by conjac glucomannan (requires GmuG) (GmuR) PubMed
  • induced by cellobiose (GmuR) PubMed
  • subject to carbon catabolite repression (CcpA) PubMed

• Regulatory mechanism:
  • GmuR: transcription repression PubMed
  • CcpA: transcription repression PubMed
  • AbrB: transcription activation PubMed

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Additional publications: PubMed