Difference between revisions of "GlnK"

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|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[glsA]]'', ''[[glnL]]''
 
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[glsA]]'', ''[[glnL]]''
 
|-
 
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|style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU02440 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU02440 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU02440 Advanced_DNA]
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|style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU02440 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU02440 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU02440 DNA_with_flanks]
 
|-
 
|-
 
|colspan="2" | '''Genetic context''' <br/> [[Image:ycbA_context.gif]]
 
|colspan="2" | '''Genetic context''' <br/> [[Image:ycbA_context.gif]]

Revision as of 09:23, 14 May 2013

Gene name glnK
Synonyms ycbA, yzgA
Essential no
Product two-component sensor kinase
Function regulation of the glsA-glnT operon
Gene expression levels in SubtiExpress: glnK
Interactions involving this protein in SubtInteract: GlnK
Metabolic function and regulation of this protein in SubtiPathways:
Ammonium/ glutamate
MW, pI 43 kDa, 5.731
Gene length, protein length 1161 bp, 387 aa
Immediate neighbours glsA, glnL
Sequences Protein DNA DNA_with_flanks
Genetic context
YcbA context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
GlnK expression.png




























Categories containing this gene/protein

biosynthesis/ acquisition of amino acids, utilization of amino acids, protein modification, transcription factors and their control, membrane proteins, phosphoproteins

This gene is a member of the following regulons

The gene

Basic information

  • Locus tag: BSU02440

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: autophosphorylation, phosphorylation of GlnL
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains: four transmembrane segments, C-terminal histidine phosphotransferase domain
  • Modification: autophosphorylation on a His residue
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [2]
  • E.C. number:

Additional information

Expression and regulation

  • Operon:
  • Sigma factor:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Takenori Satomura, Daisuke Shimura, Kei Asai, Yoshito Sadaie, Kazutake Hirooka, Yasutaro Fujita
Enhancement of glutamine utilization in Bacillus subtilis through the GlnK-GlnL two-component regulatory system.
J Bacteriol: 2005, 187(14);4813-21
[PubMed:15995196] [WorldCat.org] [DOI] (P p)

C Fabret, V A Feher, J A Hoch
Two-component signal transduction in Bacillus subtilis: how one organism sees its world.
J Bacteriol: 1999, 181(7);1975-83
[PubMed:10094672] [WorldCat.org] [DOI] (P p)