Difference between revisions of "NtdB"
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|style="background:#ABCDEF;" align="center"|'''Function''' || synthesis of the antibiotic kanosamine | |style="background:#ABCDEF;" align="center"|'''Function''' || synthesis of the antibiotic kanosamine | ||
|- | |- | ||
| − | |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http:// | + | |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU10540 ntdB] |
|- | |- | ||
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 33 kDa, 5.352 | |style="background:#ABCDEF;" align="center"| '''MW, pI''' || 33 kDa, 5.352 | ||
| Line 21: | Line 21: | ||
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[ntdC]]'', ''[[ntdA]]'' | |style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[ntdC]]'', ''[[ntdA]]'' | ||
|- | |- | ||
| − | | | + | |style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU10540 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU10540 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU10540 Advanced_DNA] |
|- | |- | ||
|colspan="2" | '''Genetic context''' <br/> [[Image:yhjK_context.gif]] | |colspan="2" | '''Genetic context''' <br/> [[Image:yhjK_context.gif]] | ||
Revision as of 12:29, 13 May 2013
- Description: kanosamine-6-phosphate phosphatase
| Gene name | ntdB |
| Synonyms | yhjK |
| Essential | no |
| Product | kanosamine-6-phosphate phosphatase |
| Function | synthesis of the antibiotic kanosamine |
| Gene expression levels in SubtiExpress: ntdB | |
| MW, pI | 33 kDa, 5.352 |
| Gene length, protein length | 858 bp, 286 aa |
| Immediate neighbours | ntdC, ntdA |
| Sequences | Protein DNA Advanced_DNA |
Genetic context 
This image was kindly provided by SubtiList
| |
Expression at a glance PubMed
| |
Contents
Categories containing this gene/protein
miscellaneous metabolic pathways, biosynthesis of antibacterial compounds
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU10540
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- kanosamine-6-phosphate --> kanosamine PubMed
- Protein family: Cof family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
Database entries
- Structure: 3GYG
- UniProt: O07565
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Reviews
Original publications
Natasha D Vetter, David M Langill, Shazia Anjum, Julie Boisvert-Martel, Rajendra C Jagdhane, Egiroh Omene, Hongyan Zheng, Karin E van Straaten, Isaac Asiamah, Ed S Krol, David A R Sanders, David R J Palmer
A previously unrecognized kanosamine biosynthesis pathway in Bacillus subtilis.
J Am Chem Soc: 2013, 135(16);5970-3
[PubMed:23586652]
[WorldCat.org]
[DOI]
(I p)
Takashi Inaoka, Takenori Satomura, Yasutaro Fujita, Kozo Ochi
Novel gene regulation mediated by overproduction of secondary metabolite neotrehalosadiamine in Bacillus subtilis.
FEMS Microbiol Lett: 2009, 291(2);151-6
[PubMed:19087206]
[WorldCat.org]
[DOI]
(I p)
Takashi Inaoka, Kozo Ochi
Glucose uptake pathway-specific regulation of synthesis of neotrehalosadiamine, a novel autoinducer produced in Bacillus subtilis.
J Bacteriol: 2007, 189(1);65-75
[PubMed:17056753]
[WorldCat.org]
[DOI]
(P p)
Takashi Inaoka, Kosaku Takahashi, Hiroshi Yada, Mitsuru Yoshida, Kozo Ochi
RNA polymerase mutation activates the production of a dormant antibiotic 3,3'-neotrehalosadiamine via an autoinduction mechanism in Bacillus subtilis.
J Biol Chem: 2004, 279(5);3885-92
[PubMed:14612444]
[WorldCat.org]
[DOI]
(P p)
