Difference between revisions of "CdaS"

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(This gene is a member of the following regulons)
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|style="background:#ABCDEF;" align="center"|'''Function''' || synthesis of c-di-AMP
 
|style="background:#ABCDEF;" align="center"|'''Function''' || synthesis of c-di-AMP
 
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://cellpublisher.gobics.de/subtiexpress/ ''Subti''Express]''': [http://cellpublisher.gobics.de/subtiexpress/bsu/BSU19430 cdaS]
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU19430 cdaS]
 
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|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 22 kDa, 5.367   
 
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 22 kDa, 5.367   
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|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[yojK]]'', ''[[yojI]]''
 
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[yojK]]'', ''[[yojI]]''
 
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|colspan="2" style="background:#FAF8CC;" align="center"|'''Get the DNA and protein [http://srs.ebi.ac.uk/srsbin/cgi-bin/wgetz?-e+&#91;EMBLCDS:CAB13835&#93;+-newId sequences] <br/> (Barbe ''et al.'', 2009)'''
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|style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU19430 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU19430 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU19430 Advanced_DNA]
 
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Revision as of 13:01, 13 May 2013

  • Description: sporulation-specific diadenylate cyclase, synthesis of c-di-AMP

Gene name cdaS
Synonyms yojJ
Essential no
Product sporulation-specific diadenylate cyclase
Function synthesis of c-di-AMP
Gene expression levels in SubtiExpress: cdaS
MW, pI 22 kDa, 5.367
Gene length, protein length 621 bp, 207 aa
Immediate neighbours yojK, yojI
Sequences Protein DNA Advanced_DNA
Genetic context
YojJ context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
YojJ expression.png















Categories containing this gene/protein

metabolism of signalling nucleotides, sporulation proteins

This gene is a member of the following regulons

SigG regulon

The gene

Basic information

  • Locus tag: BSU19430

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
    • synthesis of c-di-AMP from two molecules of ATP PubMed
  • Protein family:
  • Paralogous protein(s): CdaA

Extended information on the protein

  • Kinetic information:
  • Domains: contains a DAC domain involved in the synthesis of c-di-AMP PubMed
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure: 2FB5 (the protein of B. cereus, 48% identity, 81% similarity)
  • KEGG entry: [2]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
    • expressed late during sporulation in the forespore (SigG) PubMed
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Reviews

Original publications