Difference between revisions of "LtaS"
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|style="background:#ABCDEF;" align="center"|'''Function''' || biosynthesis of lipoteichoic acid | |style="background:#ABCDEF;" align="center"|'''Function''' || biosynthesis of lipoteichoic acid | ||
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| − | |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http:// | + | |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU07710 ltaS] |
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Metabolic function and regulation of this protein in [[SubtiPathways|''Subti''Pathways]]: <br/>[http://subtiwiki.uni-goettingen.de/pathways/fatty_acid_synthesis.html Lipid synthesis]''' | |colspan="2" style="background:#FAF8CC;" align="center"| '''Metabolic function and regulation of this protein in [[SubtiPathways|''Subti''Pathways]]: <br/>[http://subtiwiki.uni-goettingen.de/pathways/fatty_acid_synthesis.html Lipid synthesis]''' | ||
| Line 23: | Line 23: | ||
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[nagP]]'', ''[[yflD]]'' | |style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[nagP]]'', ''[[yflD]]'' | ||
|- | |- | ||
| − | | | + | |style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU07710 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU07710 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU07710 Advanced_DNA] |
|- | |- | ||
|colspan="2" | '''Genetic context''' <br/> [[Image:yflE_context.gif]] | |colspan="2" | '''Genetic context''' <br/> [[Image:yflE_context.gif]] | ||
Revision as of 12:21, 13 May 2013
- Description: polyglycerolphosphate lipoteichoic acid synthase
| Gene name | ltaS |
| Synonyms | yflE |
| Essential | no |
| Product | major lipoteichoic acid synthase |
| Function | biosynthesis of lipoteichoic acid |
| Gene expression levels in SubtiExpress: ltaS | |
| Metabolic function and regulation of this protein in SubtiPathways: Lipid synthesis | |
| MW, pI | 74 kDa, 5.202 |
| Gene length, protein length | 1947 bp, 649 aa |
| Immediate neighbours | nagP, yflD |
| Sequences | Protein DNA Advanced_DNA |
Genetic context 
This image was kindly provided by SubtiList
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Expression at a glance PubMed
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Contents
Categories containing this gene/protein
cell wall synthesis, biosynthesis of cell wall components, membrane proteins, phosphoproteins
This gene is a member of the following regulons
The gene
Basic information
- Locus tag:
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family: LTA synthase family (according to Swiss-Prot)
Extended information on the protein
- Kinetic information:
- Domains:
- Modification: phosphorylated on Thr-297 PubMed
- Cofactor(s):
- Effectors of protein activity:
Database entries
- Structure: 2W8D
- UniProt: O34952
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Operon: ltaS (according to DBTBS)
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Reviews: PubMed
Nathalie T Reichmann, Angelika Gründling
Location, synthesis and function of glycolipids and polyglycerolphosphate lipoteichoic acid in Gram-positive bacteria of the phylum Firmicutes.
FEMS Microbiol Lett: 2011, 319(2);97-105
[PubMed:21388439]
[WorldCat.org]
[DOI]
(I p)
Original publications
