Difference between revisions of "TenI"

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Revision as of 17:02, 18 September 2012

  • Description: thiazole tautomerase

Gene name tenI
Synonyms
Essential no
Product thiazole tautomerase
Function biosynthesis of thiamine
Gene expression levels in SubtiExpress: tenI
Metabolic function and regulation of this protein in SubtiPathways:
Thiamin
MW, pI 22 kDa, 8.132
Gene length, protein length 615 bp, 205 aa
Immediate neighbours tenA, thiO
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
TenI context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
TenI expression.png



















Categories containing this gene/protein

biosynthesis of cofactors

This gene is a member of the following regulons

Thi-box

The gene

Basic information

  • Locus tag: BSU11660

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: TMP-PPase family (according to Swiss-Prot)
  • Paralogous protein(s): ThiE

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Sigma factor:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Reviews

Tadhg P Begley, Steven E Ealick, Fred W McLafferty
Thiamin biosynthesis: still yielding fascinating biological chemistry.
Biochem Soc Trans: 2012, 40(3);555-60
[PubMed:22616866] [WorldCat.org] [DOI] (I p)

T P Begley, D M Downs, S E Ealick, F W McLafferty, A P Van Loon, S Taylor, N Campobasso, H J Chiu, C Kinsland, J J Reddick, J Xi
Thiamin biosynthesis in prokaryotes.
Arch Microbiol: 1999, 171(5);293-300
[PubMed:10382260] [WorldCat.org] [DOI] (P p)

Original publications