Difference between revisions of "MenE"
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|style="background:#ABCDEF;" align="center"|'''Function''' || biosynthesis of menaquinone | |style="background:#ABCDEF;" align="center"|'''Function''' || biosynthesis of menaquinone | ||
|- | |- | ||
| − | |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http:// | + | |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU30790 menE] |
|- | |- | ||
|colspan="2" style="background:#FAF8CC;" align="center"| '''Metabolic function and regulation of this protein in [[SubtiPathways|''Subti''Pathways]]: <br/>[http://subtiwiki.uni-goettingen.de/pathways/menaquinone.html Menaquinone]''' | |colspan="2" style="background:#FAF8CC;" align="center"| '''Metabolic function and regulation of this protein in [[SubtiPathways|''Subti''Pathways]]: <br/>[http://subtiwiki.uni-goettingen.de/pathways/menaquinone.html Menaquinone]''' | ||
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|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[menC]]'', ''[[menB]]'' | |style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[menC]]'', ''[[menB]]'' | ||
|- | |- | ||
| − | | | + | |style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU30790 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU30790 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU30790 Advanced_DNA] |
|- | |- | ||
|colspan="2" | '''Genetic context''' <br/> [[Image:menE_context.gif]] | |colspan="2" | '''Genetic context''' <br/> [[Image:menE_context.gif]] | ||
Revision as of 13:41, 13 May 2013
- Description: o-succinylbenzoate-CoA ligase
| Gene name | menE |
| Synonyms | |
| Essential | yes PubMed |
| Product | o-succinylbenzoate-CoA ligase |
| Function | biosynthesis of menaquinone |
| Gene expression levels in SubtiExpress: menE | |
| Metabolic function and regulation of this protein in SubtiPathways: Menaquinone | |
| MW, pI | 54 kDa, 5.466 |
| Gene length, protein length | 1458 bp, 486 aa |
| Immediate neighbours | menC, menB |
| Sequences | Protein DNA Advanced_DNA |
Genetic context 
This image was kindly provided by SubtiList
| |
Expression at a glance PubMed
| |
Contents
Categories containing this gene/protein
biosynthesis of cofactors, essential genes
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU30790
Phenotypes of a mutant
essential PubMed
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: ATP + 2-succinylbenzoate + CoA = AMP + diphosphate + 2-succinylbenzoyl-CoA (according to Swiss-Prot)
- Protein family: MenE type 1 subfamily (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
Database entries
- Structure:
- UniProt: P23971
- KEGG entry: [3]
- E.C. number: 6.2.1.26
Additional information
Expression and regulation
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Alia Lapidus, Nathalie Galleron, Alexei Sorokin, S Dusko Ehrlich
Sequencing and functional annotation of the Bacillus subtilis genes in the 200 kb rrnB-dnaB region.
Microbiology (Reading): 1997, 143 ( Pt 11);3431-3441
[PubMed:9387221]
[WorldCat.org]
[DOI]
(P p)
X Qin, H W Taber
Transcriptional regulation of the Bacillus subtilis menp1 promoter.
J Bacteriol: 1996, 178(3);705-13
[PubMed:8550504]
[WorldCat.org]
[DOI]
(P p)
J R Driscoll, H W Taber
Sequence organization and regulation of the Bacillus subtilis menBE operon.
J Bacteriol: 1992, 174(15);5063-71
[PubMed:1629163]
[WorldCat.org]
[DOI]
(P p)
