Difference between revisions of "HemN"

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|style="background:#ABCDEF;" align="center"|'''Function''' || heme biosynthesis  
 
|style="background:#ABCDEF;" align="center"|'''Function''' || heme biosynthesis  
 
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://cellpublisher.gobics.de/subtiexpress/ ''Subti''Express]''': [http://cellpublisher.gobics.de/subtiexpress/bsu/BSU25500 hemN]
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU25500 hemN]
 
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|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 41 kDa, 5.534   
 
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 41 kDa, 5.534   
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|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[hrcA]]'', ''[[lepA]]''
 
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[hrcA]]'', ''[[lepA]]''
 
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|colspan="2" style="background:#FAF8CC;" align="center"|'''Get the DNA and protein [http://srs.ebi.ac.uk/srsbin/cgi-bin/wgetz?-e+&#91;EMBLCDS:CAB14492&#93;+-newId sequences] <br/> (Barbe ''et al.'', 2009)'''
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|style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU25500 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU25500 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU25500 Advanced_DNA]
 
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Revision as of 13:21, 13 May 2013

  • Description: anaerobic coproporphyrinogen III oxidase

Gene name hemN
Synonyms yqeR
Essential no
Product anaerobic coproporphyrinogen III oxidase
Function heme biosynthesis
Gene expression levels in SubtiExpress: hemN
MW, pI 41 kDa, 5.534
Gene length, protein length 1098 bp, 366 aa
Immediate neighbours hrcA, lepA
Sequences Protein DNA Advanced_DNA
Genetic context
HemN context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
HemN expression.png
























Categories containing this gene/protein

biosynthesis of cofactors

This gene is a member of the following regulons

The gene

Basic information

  • Locus tag: BSU25500

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: Coproporphyrinogen-III + 2 S-adenosyl-L-methionine = protoporphyrinogen-IX + 2 CO2 + 2 L-methionine + 2 5'-deoxyadenosine (according to Swiss-Prot)
  • Protein family: anaerobic coproporphyrinogen III oxidase family (according to Swiss-Prot)
  • Paralogous protein(s): HemZ

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
  • Regulatory mechanism:
  • Additional information: There is a terminator between lepA and hemN with only little readthrough

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References