Difference between revisions of "LspA"

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|style="background:#ABCDEF;" align="center"|'''Function''' || protein secretion
 
|style="background:#ABCDEF;" align="center"|'''Function''' || protein secretion
 
|-
 
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://cellpublisher.gobics.de/subtiexpress/ ''Subti''Express]''': [http://cellpublisher.gobics.de/subtiexpress/bsu/BSU15450 lspA]
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU15450 lspA]
 
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Metabolic function and regulation of this protein in [[SubtiPathways|''Subti''Pathways]]: <br/>[http://subtiwiki.uni-goettingen.de/wiki/index.php/Protein_secretion Protein secretion]'''
 
|colspan="2" style="background:#FAF8CC;" align="center"| '''Metabolic function and regulation of this protein in [[SubtiPathways|''Subti''Pathways]]: <br/>[http://subtiwiki.uni-goettingen.de/wiki/index.php/Protein_secretion Protein secretion]'''
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|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[ylyA]]'', ''[[ylyB]]''
 
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[ylyA]]'', ''[[ylyB]]''
 
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|colspan="2" style="background:#FAF8CC;" align="center"|'''Get the DNA and protein [http://srs.ebi.ac.uk/srsbin/cgi-bin/wgetz?-e+&#91;EMBLCDS:CAB13419&#93;+-newId sequences] <br/> (Barbe ''et al.'', 2009)'''
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|style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU15450 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU15450 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU15450 Advanced_DNA]
 
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|colspan="2" | '''Genetic context''' <br/> [[Image:lspA_context.gif]]
 
|colspan="2" | '''Genetic context''' <br/> [[Image:lspA_context.gif]]

Revision as of 12:47, 13 May 2013

  • Description: signal peptidase II

Gene name lspA
Synonyms lsp
Essential no
Product signal peptidase II
Function protein secretion
Gene expression levels in SubtiExpress: lspA
Metabolic function and regulation of this protein in SubtiPathways:
Protein secretion
MW, pI 17 kDa, 9.133
Gene length, protein length 462 bp, 154 aa
Immediate neighbours ylyA, ylyB
Sequences Protein DNA Advanced_DNA
Genetic context
LspA context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
LspA expression.png
























Categories containing this gene/protein

protein secretion, membrane proteins

This gene is a member of the following regulons

The gene

Basic information

  • Locus tag: BSU15450

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: Release of signal peptides from bacterial membrane prolipoproteins (according to Swiss-Prot)
  • Protein family: peptidase A8 family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [2]
  • E.C. number:

Additional information

Expression and regulation

  • Operon:
  • Sigma factor:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

J Bengtsson, H Tjalsma, C Rivolta, L Hederstedt
Subunit II of Bacillus subtilis cytochrome c oxidase is a lipoprotein.
J Bacteriol: 1999, 181(2);685-8
[PubMed:9882689] [WorldCat.org] [DOI] (P p)