Difference between revisions of "LipC"

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* '''Description:''' phospholipase implicated in spore germination <br/><br/>
  
 
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|style="background:#ABCDEF;" align="center"|'''Function''' || spore germination
 
|style="background:#ABCDEF;" align="center"|'''Function''' || spore germination
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://cellpublisher.gobics.de/subtiexpress/ ''Subti''Express]''': [http://cellpublisher.gobics.de/subtiexpress/bsu/BSU04110 lipC]
 
 
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Function and regulation of this protein in [[SubtiPathways|''Subti''Pathways]]: <br/>[http://subtiwiki.uni-goettingen.de/pathways/phosphorelay.html Phosphorelay]'''
 
|colspan="2" style="background:#FAF8CC;" align="center"| '''Function and regulation of this protein in [[SubtiPathways|''Subti''Pathways]]: <br/>[http://subtiwiki.uni-goettingen.de/pathways/phosphorelay.html Phosphorelay]'''
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|colspan="2" | '''Genetic context''' <br/> [[Image:ycsK_context.gif]]
 
|colspan="2" | '''Genetic context''' <br/> [[Image:ycsK_context.gif]]
 
  <div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div>
 
  <div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div>
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|colspan="2" |'''[http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=lipC_462431_463072_1 Expression at a glance]'''&#160;&#160;&#160;{{PubMed|22383849}}<br/>[[Image:lipC_expression.png|500px]]
 
 
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** ''lipC'' (according to [http://dbtbs.hgc.jp/COG/prom/ycsFGI-kipIAR-ycsK.html DBTBS])
 
** ''lipC'' (according to [http://dbtbs.hgc.jp/COG/prom/ycsFGI-kipIAR-ycsK.html DBTBS])
  
* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=lipC_462431_463072_1 lipC] {{PubMed|22383849}}
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* '''[[Sigma factor]]:'''  
 
 
* '''Sigma factor:'''  
 
 
** ''lipC'': [[SigK]] {{PubMed|15699190,17220230}}
 
** ''lipC'': [[SigK]] {{PubMed|15699190,17220230}}
  

Revision as of 11:07, 7 August 2012

  • Description: phospholipase implicated in spore germination

Gene name lipC
Synonyms ycsK
Essential no
Product spore coat phospholipase B
Function spore germination
Function and regulation of this protein in SubtiPathways:
Phosphorelay
MW, pI 23 kDa, 5.839
Gene length, protein length 639 bp, 213 aa
Immediate neighbours kipR, yczI
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
YcsK context.gif
This image was kindly provided by SubtiList







Categories containing this gene/protein

utilization of lipids, sporulation proteins, germination

This gene is a member of the following regulons

KipR regulon, SigK regulon, TnrA regulon

The gene

Basic information

  • Locus tag: BSU04110

Phenotypes of a mutant

defective in L-alanine-stimulated germination PubMed

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: cleaves the fatty acids at the sn-1 and sn-2 positions of phospholipids PubMed
  • Protein family: 'GDSL' lipolytic enzyme family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
    • lipC: expressed four hours after onset of sporulation (GerE) PubMed
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References