Difference between revisions of "HemE"
| Line 1: | Line 1: | ||
| − | + | ||
{| align="right" border="1" cellpadding="2" | {| align="right" border="1" cellpadding="2" | ||
| Line 13: | Line 13: | ||
|- | |- | ||
|style="background:#ABCDEF;" align="center"|'''Function''' || heme biosynthesis | |style="background:#ABCDEF;" align="center"|'''Function''' || heme biosynthesis | ||
| + | |- | ||
| + | |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://cellpublisher.gobics.de/subtiexpress/ ''Subti''Express]''': [http://cellpublisher.gobics.de/subtiexpress/bsu/BSU10120 hemE] | ||
|- | |- | ||
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 39 kDa, 5.262 | |style="background:#ABCDEF;" align="center"| '''MW, pI''' || 39 kDa, 5.262 | ||
Revision as of 16:26, 6 August 2012
| Gene name | hemE |
| Synonyms | |
| Essential | no |
| Product | uroporphyrinogen decarboxylase (uroporphyrinogen III) |
| Function | heme biosynthesis |
| Gene expression levels in SubtiExpress: hemE | |
| MW, pI | 39 kDa, 5.262 |
| Gene length, protein length | 1059 bp, 353 aa |
| Immediate neighbours | pbpF, hemH |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
| |
Expression at a glance PubMed
| |
Contents
Categories containing this gene/protein
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU10120
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: Uroporphyrinogen III = coproporphyrinogen + 4 CO2 (according to Swiss-Prot)
- Protein family: uroporphyrinogen decarboxylase family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Localization:
- cytoplasm (according to Swiss-Prot)
Database entries
- Structure: 2INF
- UniProt: P32395
- KEGG entry: [3]
- E.C. number: 4.1.1.37
Additional information
Expression and regulation
- Sigma factor:
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
M Hansson, L Hederstedt
Cloning and characterization of the Bacillus subtilis hemEHY gene cluster, which encodes protoheme IX biosynthetic enzymes.
J Bacteriol: 1992, 174(24);8081-93
[PubMed:1459957]
[WorldCat.org]
[DOI]
(P p)
