Difference between revisions of "NadC"
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* '''Operon:''' ''[[nadB]]-[[nadC]]-[[nadA]]'' {{PubMed|8444804}} | * '''Operon:''' ''[[nadB]]-[[nadC]]-[[nadA]]'' {{PubMed|8444804}} | ||
− | * '''[ | + | * '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=nadC_2847048_2847917_-1 nadC] {{PubMed|22383849}} |
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+ | * '''Sigma factor:''' [[SigA]] {{PubMed|8444804}} | ||
* '''Regulation:''' | * '''Regulation:''' | ||
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** [[NadR]]: transcription repression [http://www.ncbi.nlm.nih.gov/sites/entrez/16199587 PubMed] | ** [[NadR]]: transcription repression [http://www.ncbi.nlm.nih.gov/sites/entrez/16199587 PubMed] | ||
− | * '''Additional information:''' | + | * '''Additional information:''' |
=Biological materials = | =Biological materials = |
Revision as of 14:17, 16 April 2012
- Description: nicotinate-nucleotide diphosphorylase (carboxylating)
Gene name | nadC |
Synonyms | yrxB |
Essential | no |
Product | nicotinate-nucleotide diphosphorylase (carboxylating) |
Function | NAD biosynthesis |
MW, pI | 31 kDa, 5.18 |
Gene length, protein length | 867 bp, 289 aa |
Immediate neighbours | nadA, nadB |
Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context This image was kindly provided by SubtiList
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Contents
Categories containing this gene/protein
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU27860
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: Nicotinate D-ribonucleotide + diphosphate + CO2 = pyridine-2,3-dicarboxylate + 5-phospho-alpha-D-ribose 1-diphosphate (according to Swiss-Prot)
- Protein family: nadC/modD family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Localization: cytoplasm (according to Swiss-Prot)
Database entries
- Structure:
- UniProt: P39666
- KEGG entry: [3]
- E.C. number: 2.4.2.19
Additional information
Expression and regulation
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References