Difference between revisions of "Tpi"
(→The gene) |
|||
Line 1: | Line 1: | ||
− | * '''Description:''' | + | * '''Description:''' triose phosphate isomerase, glycolytic/ gluconeogenic enzyme<br/><br/> |
{| align="right" border="1" cellpadding="2" | {| align="right" border="1" cellpadding="2" | ||
Line 10: | Line 10: | ||
|style="background:#ABCDEF;" align="center"| '''Essential''' || yes | |style="background:#ABCDEF;" align="center"| '''Essential''' || yes | ||
|- | |- | ||
− | |style="background:#ABCDEF;" align="center"| '''Product''' || | + | |style="background:#ABCDEF;" align="center"| '''Product''' || triosephosphate isomerase |
|- | |- | ||
− | |style="background:#ABCDEF;" align="center"|'''Function''' || | + | |style="background:#ABCDEF;" align="center"|'''Function''' || enzyme in glycolysis/ gluconeogenesis |
|- | |- | ||
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 26,9 kDa, 4.79 | |style="background:#ABCDEF;" align="center"| '''MW, pI''' || 26,9 kDa, 4.79 |
Revision as of 12:54, 13 January 2009
- Description: triose phosphate isomerase, glycolytic/ gluconeogenic enzyme
Gene name | tpi |
Synonyms | tpiA |
Essential | yes |
Product | triosephosphate isomerase |
Function | enzyme in glycolysis/ gluconeogenesis |
MW, pI | 26,9 kDa, 4.79 |
Gene length, protein length | 759 bp, 253 amino acids |
Immediate neighbours | pgk, pgm |
Gene sequence (+200bp) | Protein sequence |
Genetic context |
Contents
The gene
Basic information
- Coordinates: 3478439 - 3479197
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: D-glyceraldehyde 3-phosphate = glycerone phosphate
- Protein family: triosephosphate isomerase family
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification: phosphorylation (STY) PubMed
- Cofactor(s):
- Effectors of protein activity:
- Interactions: Pgm-TpiA
- Localization: cytoplasm PubMed
Database entries
- Structure: complex with 2-phosphpoglycolic acid, Geobacillus stearothermophilus NCBI
- Swiss prot entry: [3]
- KEGG entry: [4]
- E.C. number: [5]
Additional information
Expression and regulation
- Sigma factor: SigA
- Additional information:
Biological materials
Labs working on this gene/protein
Your additional remarks
References
- Ludwig, H., Homuth, G., Schmalisch, M., Dyka, F. M., Hecker, M., and Stülke, J. (2001) Transcription of glycolytic genes and operons in Bacillus subtilis: evidence for the presence of multiple levels of control of the gapA operon. Mol Microbiol 41, 409-422.PubMed