Difference between revisions of "RapF"
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| − | * '''Description:''' [[response regulator aspartate phosphatase]], controls [[ComA]] activity <br/><br/> | + | * '''Description:''' [[response regulator aspartate phosphatase]], anti-activator protein, controls [[ComA]] activity <br/><br/> |
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=== Additional information=== | === Additional information=== | ||
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* '''Cofactor(s):''' | * '''Cofactor(s):''' | ||
| − | * '''Effectors of protein activity:''' binding of [[PhrF]] to [[RapF]] prevents it from binding [[ComA]] {{PubMed|15968044}} | + | * '''Effectors of protein activity:''' binding of [[PhrF]] to [[RapF]] results in a conformational change of [[RapF]] and prevents it from binding [[ComA]] {{PubMed|15968044,22215984}} |
* '''[[SubtInteract|Interactions]]:''' | * '''[[SubtInteract|Interactions]]:''' | ||
| − | ** [[RapF]]-[[ComA]] {{PubMed|15968044}} | + | ** [[RapF]]-[[ComA]] {{PubMed|15968044,22215984}} |
| − | ** [[RapF]]-[[PhrF]] {{PubMed|15968044}} | + | ** [[RapF]]-[[PhrF]] {{PubMed|15968044,22215984}} |
* '''[[Localization]]:''' | * '''[[Localization]]:''' | ||
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* '''Structure:''' | * '''Structure:''' | ||
| + | ** [http://www.rcsb.org/pdb/explore.do?structureId=3ULQ 3ULQ] (structure of the complex between the DNA-binding C-terminal domain of [[ComA]] with [[RapF]]) {{PubMed|22215984}} | ||
* '''UniProt:''' [http://www.uniprot.org/uniprot/P71002 P71002] | * '''UniProt:''' [http://www.uniprot.org/uniprot/P71002 P71002] | ||
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=References= | =References= | ||
| − | <pubmed>12850135, 15968044 11466295 16091051 </pubmed> | + | <pubmed>12850135, 15968044 11466295 16091051 22215984</pubmed> |
[[Category:Protein-coding genes]] | [[Category:Protein-coding genes]] | ||
Revision as of 09:04, 5 January 2012
- Description: response regulator aspartate phosphatase, anti-activator protein, controls ComA activity
| Gene name | rapF |
| Synonyms | ywhJ |
| Essential | no |
| Product | response regulator aspartate phosphatase |
| Function | control of ComA activity |
| Interactions involving this protein in SubtInteract: RapF | |
| MW, pI | 45 kDa, 5.18 |
| Gene length, protein length | 1143 bp, 381 aa |
| Immediate neighbours | ywhK, phrF |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
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Contents
Categories containing this gene/protein
genetic competence, protein modification, transcription factors and their control, quorum sensing
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU37460
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Protein family: RAP family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity: binding of PhrF to RapF results in a conformational change of RapF and prevents it from binding ComA PubMed
Database entries
- Structure:
- UniProt: P71002
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
