Difference between revisions of "PhrF"

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(Extended information on the protein)
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* '''Description:''' [[response regulator aspartate phosphatase]] ([[RapF]]) regulator <br/><br/>
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* '''Description:''' [[response regulator aspartate phosphatase]] ([[RapF]]) regulator, antagonizes the [[RapF]]-[[ComA]] interaction <br/><br/>
  
 
{| align="right" border="1" cellpadding="2"  
 
{| align="right" border="1" cellpadding="2"  
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=== Additional information===
 
=== Additional information===
 
 
  
  
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* '''[[SubtInteract|Interactions]]:'''
 
* '''[[SubtInteract|Interactions]]:'''
** [[RapF]]-[[PhrF]] {{PubMed|15968044}}
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** [[RapF]]-[[PhrF]] {{PubMed|15968044,22215984}}
  
 
* '''[[Localization]]:'''
 
* '''[[Localization]]:'''
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* '''Regulation:'''  
 
* '''Regulation:'''  
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** PhrF accumulates at high cell density
  
 
* '''Regulatory mechanism:'''  
 
* '''Regulatory mechanism:'''  
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=References=
 
=References=
  
<pubmed>16816200,15968044, 11466295 16091051 </pubmed>
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<pubmed>16816200,15968044, 11466295 16091051 22215984</pubmed>
  
 
[[Category:Protein-coding genes]]
 
[[Category:Protein-coding genes]]

Revision as of 09:04, 5 January 2012

Gene name phrF
Synonyms ywhI
Essential no
Product phosphatase (RapF) regulator
Function control of ComA activity
Interactions involving this protein in SubtInteract: PhrF
MW, pI 4 kDa, 10.237
Gene length, protein length 117 bp, 39 aa
Immediate neighbours rapF, ywhH
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
PhrF context.gif
This image was kindly provided by SubtiList



Categories containing this gene/protein

genetic competence, transcription factors and their control, quorum sensing, short peptides

This gene is a member of the following regulons

ComA regulon, SigH regulon

The gene

Basic information

  • Locus tag: BSU37470

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: binds to RapF, this results in the inability of RapF to interact with ComA PubMed
  • Protein family: phr family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
    • PhrF accumulates at high cell density
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References