Difference between revisions of "RapH"

From SubtiWiki
Jump to: navigation, search
(Extended information on the protein)
(Expression and regulation)
Line 112: Line 112:
 
=Expression and regulation=
 
=Expression and regulation=
  
* '''Operon:''' ''rapH'' {{PubMed|16553878}}  
+
* '''Operon:''' ''[[rapH]]-[[phrH]]'' {{PubMed|21908671}}  
  
* '''[[Sigma factor]]:'''  
+
* '''[[Sigma factor]]:''' [[SigA]] {{PubMed|21908671}}
  
 
* '''Regulation:'''  
 
* '''Regulation:'''  

Revision as of 18:21, 16 September 2011

Gene name rapH
Synonyms yeeH, yzqA
Essential no
Product response regulator aspartate phosphatase
Function control of sporulation initiation and ComA activity
Interactions involving this protein in SubtInteract: RapH
Function and regulation of this protein in SubtiPathways:
Phosphorelay
MW, pI 49 kDa, 6.121
Gene length, protein length 1293 bp, 431 aa
Immediate neighbours yeeG, phrH
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
RapH context.gif
This image was kindly provided by SubtiList







Categories containing this gene/protein

protein modification, transcription factors and their control, phosphorelay, quorum sensing

This gene is a member of the following regulons

AbrB regulon, ComK regulon, RghR regulon

The gene

Basic information

  • Locus tag: BSU06830

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
    • binds to and thereby inhibits ComA activity PubMed
    • RapH dephosphorylates Spo0F-P and thereby controls the phosphorelay PubMed
    • in addition to dephosphorylating Spo0F, RapH can antagonize sporulation by sterically blocking phosphoryl transfer to and from Spo0F PubMed
  • Protein family: RAP family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Additional publications: PubMed