Difference between revisions of "Noc"
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| − | * '''Description:''' DNA-binding protein, spatial regulator of cell division to protect the nucleoid, and timing device with an important role in the coordination of chromosome segregation and cell division<br/><br/> | + | * '''Description:''' DNA-binding protein, spatial regulator of cell division to protect the nucleoid, and timing device with an important role in the coordination of chromosome segregation and cell division, [[Noc]] and the Min system ensure the efficient utilization of the division site at midcell in by ensuring [[FtsZ|Z ring]] placement<br/><br/> |
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<pubmed> 19680248 19884039 </pubmed> | <pubmed> 19680248 19884039 </pubmed> | ||
==Original Publications== | ==Original Publications== | ||
| − | <pubmed>16549676,11807071,19494834,15210112,11948146 , </pubmed> | + | <pubmed>16549676,11807071,19494834,15210112,11948146 , 22457634</pubmed> |
[[Category:Protein-coding genes]] | [[Category:Protein-coding genes]] | ||
Revision as of 09:04, 30 March 2012
- Description: DNA-binding protein, spatial regulator of cell division to protect the nucleoid, and timing device with an important role in the coordination of chromosome segregation and cell division, Noc and the Min system ensure the efficient utilization of the division site at midcell in by ensuring Z ring placement
| Gene name | noc |
| Synonyms | yyaA |
| Essential | no |
| Product | effector of nucleoid occlusion |
| Function | control of cell division |
| MW, pI | 32 kDa, 5.812 |
| Gene length, protein length | 849 bp, 283 aa |
| Immediate neighbours | yyaB, rsmG |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
| |
Contents
Categories containing this gene/protein
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU40990
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: binds specific sites on the chromosome PubMed
- Protein family: ParB family (according to Swiss-Prot)
- Paralogous protein(s): Spo0J
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Localization: cytoplasm (according to Swiss-Prot)
Database entries
- Structure:
- UniProt: P37524
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Regulation:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion: available in the Jeff Errington lab
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Jeff Errington, Newcastle, UK Homepage
Your additional remarks
References
Reviews
Marc Bramkamp, Suey van Baarle
Division site selection in rod-shaped bacteria.
Curr Opin Microbiol: 2009, 12(6);683-8
[PubMed:19884039]
[WorldCat.org]
[DOI]
(I p)
David W Adams, Jeff Errington
Bacterial cell division: assembly, maintenance and disassembly of the Z ring.
Nat Rev Microbiol: 2009, 7(9);642-53
[PubMed:19680248]
[WorldCat.org]
[DOI]
(I p)
Original Publications
