Difference between revisions of "CypC"

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|style="background:#ABCDEF;" align="center"| '''Product''' || fatty acid beta-hydroxylating [[cytochrome P450]]
 
|style="background:#ABCDEF;" align="center"| '''Product''' || fatty acid beta-hydroxylating [[cytochrome P450]]
 
|-
 
|-
|style="background:#ABCDEF;" align="center"|'''Function''' || biosynthesis of beta-hydroxy fatty acid
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|style="background:#ABCDEF;" align="center"|'''Function''' || biosynthesis of beta-hydroxy fatty acid for lipopeptides
 
|-
 
|-
 
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 47 kDa, 6.468   
 
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 47 kDa, 6.468   

Revision as of 08:42, 16 June 2011

  • Description: long chain-fatty acid beta-hydroxylating cytochrome P450, H(2)O(2)-dependent, hydroxylates myristic acid to beta-hydroxymyristic acid

Gene name cypC
Synonyms ybdT
Essential no
Product fatty acid beta-hydroxylating cytochrome P450
Function biosynthesis of beta-hydroxy fatty acid for lipopeptides
MW, pI 47 kDa, 6.468
Gene length, protein length 1251 bp, 417 aa
Immediate neighbours ybxI, ybyB
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
CypC context.gif
This image was kindly provided by SubtiList





Categories containing this gene/protein

general stress proteins (controlled by SigB), electron transport/ other, lipid metabolism/ other

This gene is a member of the following regulons

SigB regulon

The gene

Basic information

  • Locus tag: BSU02100

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
    • hydroxylation of a long-chain fatty acid (e.g. myristic acid) at the alpha- and beta-positions using hydrogen peroxide as an oxidant PubMed
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization:

Database entries

  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Operon: cypC (according to DBTBS)
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Additional publications: PubMed