Difference between revisions of "Epr"
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| + | = [[Categories]] containing this gene/protein = | ||
| + | {{SubtiWiki category|[[utilization of nitrogen sources other than amino acids]]}}, | ||
| + | {{SubtiWiki category|[[proteolysis]]}}, | ||
| + | {{SubtiWiki category|[[motility and chemotaxis]]}} | ||
| + | |||
| + | = This gene is a member of the following [[regulons]] = | ||
| + | {{SubtiWiki regulon|[[DegU regulon]]}}, | ||
| + | {{SubtiWiki regulon|[[ScoC regulon]]}}, | ||
| + | {{SubtiWiki regulon|[[SigD regulon]]}}, | ||
| + | {{SubtiWiki regulon|[[SinR regulon]]}} | ||
=The gene= | =The gene= | ||
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=The protein= | =The protein= | ||
Revision as of 00:43, 9 December 2010
- Description: minor extracellular serine protease, involved in control of swarming motility PubMed
| Gene name | epr |
| Synonyms | ipa-15r |
| Essential | no |
| Product | minor extracellular serine protease |
| Function | protein degradation |
| MW, pI | 69 kDa, 9.875 |
| Gene length, protein length | 1935 bp, 645 aa |
| Immediate neighbours | ywbA, sacX |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
| |
Contents
Categories containing this gene/protein
utilization of nitrogen sources other than amino acids, proteolysis, motility and chemotaxis
This gene is a member of the following regulons
DegU regulon, ScoC regulon, SigD regulon, SinR regulon
The gene
Basic information
- Locus tag: BSU38400
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family: peptidase S8 family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Interactions:
- Localization: secreted (according to Swiss-Prot), extracellular (signal peptide) PubMed
Database entries
- Structure:
- UniProt: P16396
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Reviews
Massimiliano Marvasi, Pieter T Visscher, Lilliam Casillas Martinez
Exopolymeric substances (EPS) from Bacillus subtilis: polymers and genes encoding their synthesis.
FEMS Microbiol Lett: 2010, 313(1);1-9
[PubMed:20735481]
[WorldCat.org]
[DOI]
(I p)
Original publications
Monica Gupta, Kestur Krishnamurthy Rao
Epr plays a key role in DegU-mediated swarming motility of Bacillus subtilis.
FEMS Microbiol Lett: 2009, 295(2);187-94
[PubMed:19416356]
[WorldCat.org]
[DOI]
(I p)
Birgit Voigt, Haike Antelmann, Dirk Albrecht, Armin Ehrenreich, Karl-Heinz Maurer, Stefan Evers, Gerhard Gottschalk, Jan Maarten van Dijl, Thomas Schweder, Michael Hecker
Cell physiology and protein secretion of Bacillus licheniformis compared to Bacillus subtilis.
J Mol Microbiol Biotechnol: 2009, 16(1-2);53-68
[PubMed:18957862]
[WorldCat.org]
[DOI]
(I p)
Prashant Kodgire, Madhulika Dixit, K Krishnamurthy Rao
ScoC and SinR negatively regulate epr by corepression in Bacillus subtilis.
J Bacteriol: 2006, 188(17);6425-8
[PubMed:16923912]
[WorldCat.org]
[DOI]
(P p)
Madhulika Dixit, Charuta S Murudkar, K Krishnamurthy Rao
Epr is transcribed from a final sigma(D) promoter and is involved in swarming of Bacillus subtilis.
J Bacteriol: 2002, 184(2);596-9
[PubMed:11751842]
[WorldCat.org]
[DOI]
(P p)
A Sloma, A Ally, D Ally, J Pero
Gene encoding a minor extracellular protease in Bacillus subtilis.
J Bacteriol: 1988, 170(12);5557-63
[PubMed:3142851]
[WorldCat.org]
[DOI]
(P p)
