Difference between revisions of "MenB"

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(Database entries)
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= Categories containing this gene/protein =
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{{SubtiWiki category|[[biosynthesis of cofactors]]}},
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{{SubtiWiki category|[[essential genes]]}}
 
=The protein=
 
=The protein=
  

Revision as of 17:54, 30 November 2010

  • Description: naphthoate synthase

Gene name menB
Synonyms
Essential yes PubMed
Product naphthoate synthase
Function biosynthesis of menaquinone
Metabolic function and regulation of this protein in SubtiPathways:
Menaquinone
MW, pI 29 kDa, 5.343
Gene length, protein length 813 bp, 271 aa
Immediate neighbours menE, ytxM
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
MenB context.gif
This image was kindly provided by SubtiList







The gene

Basic information

  • Locus tag: BSU30800

Phenotypes of a mutant

essential PubMed

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

Categories containing this gene/protein

biosynthesis of cofactors, essential genes

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: o-succinylbenzoyl-CoA = CoA + 1,4-dihydroxy-2-naphthoate (according to Swiss-Prot)
  • Protein family: enoyl-CoA hydratase/isomerase family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization:

Database entries

  • Structure: 1RJM (from Mycobacterium tuberculosis, 48% identity, 61% similarity)
  • KEGG entry: [3]

Additional information

Expression and regulation

  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References