Difference between revisions of "PanB"

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= Categories containing this gene/protein =
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{{SubtiWiki category|[[biosynthesis of cofactors]]}}
 
=The protein=
 
=The protein=
  

Revision as of 18:37, 30 November 2010

  • Description: 3-methyl-2-oxobutanoate hydroxymethyltransferase

Gene name panB
Synonyms
Essential no
Product 3-methyl-2-oxobutanoate hydroxymethyltransferase
Function biosynthesis of coenzyme A
Metabolic function and regulation of this protein in SubtiPathways:
Coenzyme A
MW, pI 29 kDa, 5.282
Gene length, protein length 831 bp, 277 aa
Immediate neighbours panC, birA
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
PanB context.gif
This image was kindly provided by SubtiList







The gene

Basic information

  • Locus tag: BSU22430

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

Categories containing this gene/protein

biosynthesis of cofactors

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: 5,10-methylenetetrahydrofolate + 3-methyl-2-oxobutanoate + H2O = tetrahydrofolate + 2-dehydropantoate (according to Swiss-Prot)
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization: cytoplasm (according to Swiss-Prot)

Database entries

  • Structure: 3EZ4 (from Burkholderia pseudomallei, 44% identity, 64% similarity)
  • KEGG entry: [2]

Additional information

Expression and regulation

  • Operon:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References