Difference between revisions of "T-box"

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(Complete list of genes controlled by T-box elements)
(Reviews on T-box regulation)
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==Reviews on T-box regulation==
 
==Reviews on T-box regulation==
  
<pubmed> 19258532,7527891, 11917026 ,8348614,17381302 10546897 </pubmed>
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<pubmed> 19258532,7527891, 11917026 ,8348614,17381302 10546897 19932103 </pubmed>

Revision as of 08:24, 5 February 2010

The T-box element is an RNA switch that controls genes involved in amino acid metabolism.

In the absence of an amino acid, the uncharged tRNA binds the T-box region in the leader region of the mRNA of the controlled gene/ operon and thereby prevents the formation of a transcription terminator. The result is gene expression of the target gene in the absence of the specific amino acid.

Complete list of genes controlled by T-box elements

  • Induction by alanine limitation
  • Induction by aspartate limitation
  • Induction by histidine limitation
  • Induction by phenyalanine limitation
  • Induction by serine limitation
  • Induction by tyrosine limitation

Structure of a T-box ribowsitch

Melinda S Gerdeman, Tina M Henkin, Jennifer V Hines
Solution structure of the Bacillus subtilis T-box antiterminator RNA: seven nucleotide bulge characterized by stacking and flexibility.
J Mol Biol: 2003, 326(1);189-201
[PubMed:12547201] [WorldCat.org] [DOI] (P p)


Reviews on T-box regulation