ComFC

• Description: late competence gene
  
  

Gene name	comFC
Synonyms
Essential	no
Product	unknown
Function	compentence
MW, pI	26 kDa, 8.851
Gene length, protein length	687 bp, 229 aa
Immediate neighbours	yvyF, comFB
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList

The gene

Basic information

• Locus tag: BSU35450

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

Categories containing this gene/protein

genetic competence

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family: comF/gntX family (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:

Database entries

• Structure:

• UniProt: P39147

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: comFA-comFB-comFC-yvyF-flgM-yvyG-flgK-flgL PubMed

• Sigma factor: comFA: SigA PubMed

• Regulation:

• Regulatory mechanism:
  • ComK: transcription activation PubMed

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Hanne Jarmer, Randy Berka, Steen Knudsen, Hans H Saxild
Transcriptome analysis documents induced competence of Bacillus subtilis during nitrogen limiting conditions.
FEMS Microbiol Lett: 2002, 206(2);197-200
[PubMed:11814663] [WorldCat.org] [DOI] (P p)

J A Londoño-Vallejo, D Dubnau
comF, a Bacillus subtilis late competence locus, encodes a protein similar to ATP-dependent RNA/DNA helicases.
Mol Microbiol: 1993, 9(1);119-31
[PubMed:8412657] [WorldCat.org] [DOI] (P p)