Difference between revisions of "AraE"
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=== Database entries === | === Database entries === | ||
| − | * '''DBTBS entry:''' | + | * '''DBTBS entry:''' [http://dbtbs.hgc.jp/COG/prom/araE.html] |
* '''SubtiList entry:''' [http://genolist.pasteur.fr/SubtiList/genome.cgi?gene_detail+BG11907] | * '''SubtiList entry:''' [http://genolist.pasteur.fr/SubtiList/genome.cgi?gene_detail+BG11907] | ||
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* '''Regulation:''' | * '''Regulation:''' | ||
| − | ** repressed by glucose ([[CcpA]]) {{PubMed| | + | ** repressed by glucose ([[CcpA]]) {{PubMed|12949161}} |
** induced by arabinose ([[AraR]]) {{PubMed|9401028,9620981,10417639}} | ** induced by arabinose ([[AraR]]) {{PubMed|9401028,9620981,10417639}} | ||
* '''Regulatory mechanism:''' | * '''Regulatory mechanism:''' | ||
| − | ** [[CcpA]]: transcription repression | + | ** [[CcpA]]: transcription repression {{PubMed|12949161}} |
** [[AraR]]: transcription repression {{PubMed|9401028,9620981,10417639}} | ** [[AraR]]: transcription repression {{PubMed|9401028,9620981,10417639}} | ||
| Line 124: | Line 124: | ||
=References= | =References= | ||
| − | <pubmed>9401028,9620981,,10417639,9620981 | + | <pubmed>9401028,9620981,,10417639,9620981 12949161, </pubmed> |
[[Category:Protein-coding genes]] | [[Category:Protein-coding genes]] | ||
Revision as of 11:00, 29 December 2009
- Description: L-arabinose permease
| Gene name | araE |
| Synonyms | yvbR |
| Essential | no |
| Product | L-arabinose permease |
| Function | uptake of arabinose, galactose and xylose |
| Metabolic function and regulation of this protein in SubtiPathways: Sugar catabolism | |
| MW, pI | 50 kDa, 9.259 |
| Gene length, protein length | 1392 bp, 464 aa |
| Immediate neighbours | cggR, araR |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
| |
Contents
The gene
Basic information
- Locus tag: BSU33960
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: transports arabinose, and also xylose and galactose PubMed
- Protein family:
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Interactions:
- Localization: cell membrane (according to Swiss-Prot)
Database entries
- Structure:
- UniProt: P96710
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Operon: araE PubMed
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
José Manuel Inácio, Carla Costa, Isabel de Sá-Nogueira
Distinct molecular mechanisms involved in carbon catabolite repression of the arabinose regulon in Bacillus subtilis.
Microbiology (Reading): 2003, 149(Pt 9);2345-2355
[PubMed:12949161]
[WorldCat.org]
[DOI]
(P p)
L J Mota, P Tavares, I Sá-Nogueira
Mode of action of AraR, the key regulator of L-arabinose metabolism in Bacillus subtilis.
Mol Microbiol: 1999, 33(3);476-89
[PubMed:10417639]
[WorldCat.org]
[DOI]
(P p)
O Krispin, R Allmansberger
The Bacillus subtilis AraE protein displays a broad substrate specificity for several different sugars.
J Bacteriol: 1998, 180(12);3250-2
[PubMed:9620981]
[WorldCat.org]
[DOI]
(P p)
I Sá-Nogueira, S S Ramos
Cloning, functional analysis, and transcriptional regulation of the Bacillus subtilis araE gene involved in L-arabinose utilization.
J Bacteriol: 1997, 179(24);7705-11
[PubMed:9401028]
[WorldCat.org]
[DOI]
(P p)
