Difference between revisions of "PucE"

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(Expression and regulation)
(Expression and regulation)
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=Expression and regulation=
 
=Expression and regulation=
 
 
* '''Operon:''' ''[[pucA]]-[[pucB]]-[[pucC]]-[[pucD]]-[[pucE]]'' {{PubMed|12823818}}  
 
* '''Operon:''' ''[[pucA]]-[[pucB]]-[[pucC]]-[[pucD]]-[[pucE]]'' {{PubMed|12823818}}  
  

Revision as of 15:33, 28 December 2009

  • Description: xanthine dehydrogenase

Gene name pucE
Synonyms yurB
Essential no
Product xanthine dehydrogenase
Function purine utilization
Metabolic function and regulation of this protein in SubtiPathways:
Purine catabolism, Nucleotides (regulation)
MW, pI 18 kDa, 6.127
Gene length, protein length 519 bp, 173 aa
Immediate neighbours pucM, pucD
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
PucE context.gif
This image was kindly provided by SubtiList







The gene

Basic information

  • Locus tag: BSU32470

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: Xanthine + NAD+ + H2O = urate + NADH (according to Swiss-Prot)
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization:

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
    • repressed by purine nucleotides (effector: allantoin) (PucR) PubMed
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References